IP Library Granted Patent US 7,617,743
Granted Patent B2
US 7,617,743 · App. 11/530,387 · Granted Nov 17, 2009

Device and method for distributing measurement sample and cleaning tubes

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Quick Facts
Patent No.
US 7,617,743
App. No.
11/530,387
Granted
Nov 17, 2009
Kind
B2
Abstract

Disclosed are a device and a method for distributing measurement sample and cleaning tubes. The device comprises a diluent container for accommodating a diluent therein; an aspirating tube for sucking a measurement sample; a first syringe for quantifying the measurement sample; a second syringe for quantifying the diluent; a first switching unit for switching between a first passage and a second passage; a bath; a sample buffer tube communicated with the first syringe; a dispensing tube for dispensing the measurement sample or the diluent into the bath; a second switching unit for switching between a third passage and a fourth passage. A reagent buffer tube, a reagent container and a third switching unit may be further provided between the sample buffer tube and the first syringe, or between the second switching unit and the input port of the dispensing tube.

Claims (39)

1. A device for distributing measurement sample and cleaning the measurement sample after analysis, the device comprising:

a diluent container;

an aspirating tube for retrieving a measurement sample;

a first syringe and a second syringe both of which are configured to be driven by a power unit for controlling a flow of the measurement sample, a lysing reagent, and the diluent according to a drive direction of the power unit;

a first switching unit configured to connect the first syringe to the second syringe or to connect the second syringe to the diluent container for controlling a flow of the measurement sample, the lysing reagent, or the diluent; and

a second switching unit configured to connect the aspirating tube to a sample buffer tube or to connect the a dispensing tube to the sample buffer tube for controlling a flow of the measurement, the lysing reagent, or the diluent.

2. The device according to claim 1 , wherein a reagent buffer tube, a reagent container for accommodating a reagent therein and a third switching unit are further provided between the sample buffer tube and the first syringe;

the reagent buffer tube is connected to the first syringe; and

the third switching unit is configured to switch among connections which comprise connecting the reagent buffer port to the sample buffer tube and connecting the reagent buffer tube to the reagent container.

3. The device according to claim 1 , wherein a reagent buffer tube, a reagent container for accommodating a reagent therein and a third switching unit are further provided between the second switching unit and the input port of the dispensing tube;

the reagent buffer tube is connected to the second switching unit; and

the third switching unit is configured to switch among connections which comprise connecting the reagent buffer tube to the dispensing tube and connecting the reagent buffer tube to the reagent container.

4. The device according to claim 2 , wherein the first switching unit, the second switching unit, and the third switching unit are solenoid valves.

5. The device according to claim 3 , wherein the first switching unit, the second switching unit, and the third switching unit are solenoid valves.

6. The device according to claim 2 , wherein the sample buffer tube comprises a first sample buffer tube and a second sample buffer tube which are connected in series, the first sample buffer tube is connected to the second switching unit, the second sample buffer tube is connected to the third switching unit, and an internal volume of the first sample buffer tube is smaller than an internal volume of the second sample buffer tube.

7. The device according to claim 3 , wherein the sample buffer tube comprises a first sample buffer tube and a second sample buffer tube which are connected in series, the first sample buffer tube is connected to the second switching unit, the second sample buffer tube is connected to the first syringe, and an internal volume of the first sample buffer tube is smaller than an internal volume of the second sample buffer tube.

8. The device according to claim 1 , wherein a pushing bar of the first syringe and a pushing bar of the second syringe are synchronously moved by the power unit.

9. The device according to claim 1 , wherein a capacity of the first syringe is smaller than that of the second syringe, and the capacity of the second syringe is larger than that of the aspirating tube.

10. A device for distributing measurement sample and cleaning the measurement sample after analysis, the device comprising:

a diluent container;

an aspirating tube for retrieving a measurement sample;

a first syringe and a second syringe both of which are configured to be driven by a power unit for controlling a flow of the measurement sample, a lysing reagent, and the diluent according to a drive direction of the power unit;

a first switching unit configured to switch among connections which comprise connecting the first syringe to the second syringe and connecting the second syringe to the diluent container for controlling a flow of the measurement, the lysing reagent, or the diluent; and

a second switching unit configured to switch among connections which comprise connecting the aspirating tube to a sample buffer tube and connecting a dispensing tube to the sample buffer tube for controlling a flow of the measurement, the lysing reagent, or the diluent, wherein

the device further comprises a reagent buffer tube, a reagent container for accommodating a reagent therein, and a third switching unit located between a sample buffer tube and the first syringe,

the reagent buffer tube is connected to a port of the first syringe,

the third switching unit is configured to switch among connections which comprise connecting the reagent buffer port to the sample buffer tube and connecting the reagent buffer tube to the reagent container, and

the sample buffer tube comprises a first sample buffer tube and a second sample buffer tube which are connected in series, wherein

the first sample buffer tube is connected to the second switching unit, the second sample buffer tube is connected to the third switching unit, and an internal volume of the first sample buffer tube is smaller than an internal volume of the second sample buffer tube.

11. A device for distributing measurement sample and cleaning the measurement sample after analysis, the device comprising:

a diluent container;

an aspirating tube for retrieving a measurement sample;

a first syringe and a second syringe both of which are configured to be driven by a power unit for controlling a flow of the measurement sample, a lysing reagent, and the diluent according to a drive direction of the power unit;

a first switching unit configured to switch among connections which comprise connecting the first syringe to the second syringe and connecting the second syringe to the diluent container for controlling a flow of the measurement, the lysing reagent, or the diluent; and

a second switching unit configured to switch among connections which comprise connecting the aspirating tube to the sample buffer tube and connecting the dispensing tube to a sample buffer tube for controlling a flow of the measurement, the lysing reagent, or the diluent, wherein

the device further comprises a reagent buffer tube, a reagent container for accommodating a reagent therein, and a third switching unit located between the second switching unit and the dispensing tube,

the reagent buffer tube is connected to the second switching unit;

the third switching unit is configured to switch among connections which comprise connecting the reagent buffer tube to the dispensing tube and connecting the reagent buffer tube to the reagent container, and

the sample buffer tube comprises a first sample buffer tube and a second sample buffer tube which are connected in series, wherein the first sample buffer tube is connected to the second switching unit, the second sample buffer tube is connected to the first syringe, and an internal volume of the first sample buffer tube is smaller than an internal volume of the second sample buffer tube.

Assignments (4)
LICENSE Recorded Jun 24, 2022
From: SHENZHEN MINDRAY BIOMEDICAL ELECTRONICS CO., LTD.
To: SHENZHEN MINDRAY ANIMAL MEDICAL TECHNOLOGY CO., LTD.
Reel/Frame 060440/0796 →
ASSIGNMENT OF FIFTY PERCENT (50%) OF THE ASSIGNOR ENTIRE RIGHT Recorded Nov 18, 2019
From: SHENZHEN MINDRAY SCIENTIFIC CO., LTD.
To: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
Reel/Frame 051050/0276 →
ASSIGNMENT OF 50% OF THE ASSIGNOR ENTIRE RIGHT Recorded Jul 25, 2018
From: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
To: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.; SHENZHEN MINDRAY SCIENTIFIC CO., LTD.
Reel/Frame 046624/0546 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 21, 2006
From: ZANG, YAOHUI; ZHANG, CHENG
To: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
Reel/Frame 018665/0744 →