Granted Patent
B2
US 7,977,484 · App. 11/547,420 · Granted Jul 12, 2011
Crystalline form of cyano-1-cyclopropy1-7-1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid
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Abstract
The present invention relates to the trihydrate of pradofloxacin, to a process for its preparation and to antibacterial compositions comprising them.
Claims (16)
1. A pradofloxacin trihydrate of formula (II)
2. The pradofloxacin trihydrate of claim 1 , having an X-ray powder diffractogram having the reflections
2θ (2 theta)
10.6230
14.1386
18.4032
20.9422
22.5604
22.8420
24.5165
25.8426
26.4972
26.8759
27.1231
of high and average intensity (>30% relative intensity).
3. The pradofloxacin trihydrate of claim 1 , wherein the crystal system is monoclinic, the space group is P2 1 , the dimensions of the unit cell are a=12.4790(18) Å α=90°, b=12.1275(18) Å β=111.009(6)°, c=15.010(2) Å γ=90°, and the volume is 2120.6(5) Å 3 .
Assignments (4)
CHANGE OF NAME
Recorded Feb 8, 2024
From: BAYER ANIMAL HEALTH GMBH
To: ELANCO ANIMAL HEALTH GMBH
Reel/Frame 066525/0898 →
NUNC PRO TUNC ASSIGNMENT
Recorded Feb 7, 2024
From: BAYER INTELLECTUAL PROPERTY GMBH
To: BAYER ANIMAL HEALTH GMBH
Reel/Frame 066401/0955 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Apr 1, 2013
From: BAYER ANIMAL HEALTH GMBH
To: BAYER INTELLECTUAL PROPERTY GMBH
Reel/Frame 030127/0549 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Feb 5, 2009
From: BAYER HEALTHCARE AG
To: BAYER ANIMAL HEALTH GMBH
Reel/Frame 022213/0726 →