Surfactant-free dispersions, compositions, and use in topical formulations
View Patent ↗The present invention provides for the preparation of stable surfactant-free dispersions of hydrophobic substances in low viscosity hydrophilic glyceryl polyacrylate or glyceryl polymethacrylate fluids, and topical vehicles formulated with the dispersions.
1. A dispersion comprising:
a hydrophobic dispersed phase; and
30% to 90% by weight of a hydrophilic continuous phase having a viscosity ranging from 400 to 1600 cps comprising:
water;
glyceryl polyacrylate or glyceryl polymethacrylate; and
a polyol,
wherein said dispersion is surfactant free and stable.
2. The dispersion of claim 1 , wherein the viscosity of the hydrophilic continuous phase is from about 500 cps to about 1200 cps.
3. The dispersion of claim 1 , wherein the hydrophobic dispersed phase comprises a plant, animal, paraffinic, or synthetic derived fat, butter, grease, solvent, wax, or oil, or mixtures thereof.
4. The dispersion of claim 1 , wherein the hydrophobic phase comprises a non-volatile silicone, a mineral oil, a vegetable oil, a water insoluble organic ester, a water insoluble triglyceride, or a fluorinated compound, or mixtures thereof.
5. The dispersion of claim 1 , wherein the polyol is glycerin, propylene glycol, butylene glycol, or pentylene glycol, or mixtures thereof.
6. The dispersion of claim 1 , wherein the dispersion is incorporated into a cosmetic composition.
7. The dispersion of claim 6 , wherein the cosmetic composition is formulated into a lotion, a cream, a gel, an ointment, a serum, a liquid, a fluid, a non-aerosol spray, an aerosol spray, a non-aerosol foam, or an aerosol foam.
8. A surfactant free topical vehicle comprising the dispersion of claim 1 .
9. The topical vehicle of claim 8 , further comprising a cosmetic ingredient, or a pharmaceutical active agent, or mixtures thereof.
10. The topical vehicle of claim 9 , wherein the vehicle comprises a cosmetic ingredient.
11. The topical vehicle of claim 10 , wherein said cosmetic ingredient is a preservative, a colorant, a fragrance, a pH adjuster, an antioxidant, a chelating agent, an absorbent, an exfoliant, a humectant, a skin lightening agent, a waterproofing agent, or a skin conditioning agent, or mixtures thereof.
12. The topical vehicle of claim 8 , wherein the topical vehicle further comprises a rheology modifier.
13. The topical vehicle of claim 12 wherein the rheology modifier is selected from the group consisting of sodium polyacrylate, carbomer, natural gum, natural gum derivative, clay, modified clay, cellulose, cellulose derivative, magnesium aluminum silicate, gellant gum, xanthan gum, starch, and modified starch, or mixtures thereof.
14. The topical vehicle of claim 8 , wherein said topical vehicle is a lotion, cream, gel, ointment, serum, liquid, fluid, non-aerosol spray, aerosol spray, non-aerosol foam, or aerosol foam.
15. A method of topically delivering a pharmaceutical or cosmetic active agent to skin comprising contacting the skin of a subject with a topical vehicle of claim 8 .