IP Library Granted Patent US 8,167,920
Granted Patent B2
US 8,167,920 · App. 11/552,201 · Granted May 1, 2012

Intranasal delivery of compounds that reduce intrancranial pressure

Assignee: Codman & Shurtleff, Inc.
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Quick Facts
Patent No.
US 8,167,920
App. No.
11/552,201
Granted
May 1, 2012
Kind
B2
Abstract

Increasing intranasal lymphatic circulation as a means of decreasing intracranial pressure in traumatic brain injury.

Claims (12)

1. A method of treating a patient having a raised intracranial pressure, comprising:

a) irradiating a nasal lymphatic tissue of the patient with an amount of red light of between about 0.02 J/cm 2 and 200 J/cm 2 to increase lymphatic circulation.

2. The method of claim 1 wherein the patient has hydrocephalus.

3. The method of claim 1 wherein the patient has a stroke.

4. The method of claim 1 wherein the patient has traumatic brain injury.

5. The method of claim 1 wherein the irradiation is accomplished by inserting a red light emitting probe into a nasal cavity and activating the red light probe to emit red light.

6. The method of claim 5 wherein the red light emitting probe is placed adjacent an olfactory mucosa.

7. The method of claim 5 wherein the red light emitting probe is placed adjacent lymphatics located in a submucosa of an olfactory epithelium.

8. The method of claim 5 wherein the red light emitting probe is placed adjacent lymphatics that encircle olfactory nerve trunks on an extracranial surface of a cribriform plate.

9. The method of claim 1 wherein a pain-killer is sprayed into a nasal cavity of the patient prior to irradiation.

10. The method of claim 1 wherein the amount of red light is between about 0.2 J/cm 2 and 50 J/cm 2 .

11. The method of claim 1 wherein the amount of red light is of between about 1 J/cm 2 and 10 J/cm 2 .

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 12, 2018
From: DEPUY SYNTHES PRODUCTS, INC.
To: INTEGRA LIFESCIENCES CORPORATION
Reel/Frame 045180/0382 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 1, 2018
From: DEPUY SPINE, LLC
To: HAND INNOVATIONS LLC
Reel/Frame 045074/0943 →
CHANGE OF NAME Recorded Mar 1, 2018
From: HAND INNOVATIONS LLC
To: DEPUY SYNTHES PRODUCTS, LLC
Reel/Frame 045476/0712 →
CHANGE OF NAME Recorded Mar 1, 2018
From: DEPUY SYNTHES PRODUCTS, LLC
To: DEPUY SYNTHES PRODUCTS, INC.
Reel/Frame 045479/0763 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 28, 2018
From: CODMAN & SHURTLEFF, INC.
To: DEPUY SPINE, LLC
Reel/Frame 045058/0627 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 24, 2006
From: DIMAURO, THOMAS M.; ATTAWIA, MOHAMED; LILIENFELD, SEAN; KAPUR, TERRI
To: CODMAN & SHURTLEFF, INC.
Reel/Frame 018426/0711 →
Continuity (1)
Related Publication 20070098645A1 · May 3, 2007