IP Library Granted Patent US 8,557,180
Granted Patent B2
US 8,557,180 · App. 11/559,472 · Granted Oct 15, 2013

System and method for analyzing a sample liquid

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Quick Facts
Patent No.
US 8,557,180
App. No.
11/559,472
Granted
Oct 15, 2013
Kind
B2
Abstract

The present invention provides a system for analyzing a sample liquid comprising a test tape having a plurality of test elements, a tape transport device which successively transports the test elements to a sample application site while advancing the tape, and a measuring device which scans the test elements loaded with sample liquid at a measuring site. The measuring site is located at a distance from the sample application site in the direction of tape movement. The tape transport is interrupted in order to exactly position a wetted area of the test elements carrying a sample liquid at the measuring site by means of a positioning device that responds to the presence of sample liquid on the test element.

Claims (17)

1. A system for analyzing a sample liquid having an analyte, comprising:

a test tape having a plurality of test elements;

a tape transport device which advances the test tape to successively transport the test elements to a sample application site at which the test elements are loaded with sample liquid to form a wetted area whose location on the test elements can vary from measurement to measurement, the tape transport device also advancing the test tape to successively transport the test elements to a measuring site at which the test elements are positioned for the detection of the analyte, the measuring site being spaced from the sample application site in the direction of tape movement;

a measuring device configured to detect an analyte in the test elements that are loaded with the sample liquid; and

a positioning device associated with the tape transport device and configured to detect the presence of the wetted area on the test elements as the test tape is advanced, the positioning device comprising a control unit, the control unit configured to respond to the detection of the wetted area and configured to interrupt the tape transport when the wetted area of the test elements is determined by the positioned device to be positioned at the measuring site, whereby the location of the test elements relative to the measuring site may vary from measurement to measurement as a function of the location of the wetted area on the test elements.

2. The system of claim 1 , wherein the control unit is coupled to a tape drive.

3. The system of claim 1 , wherein the positioning device comprises at least one optical detection unit which responds when the wetted area arrives at the measuring site.

4. The system of claim 1 , wherein the positioning device comprises two light sources directed to first and second spots, respectively, along a path the test tape travels, the first spot being positioned in front of a zone of the measuring device that detects the useful signal, the second spot being positioned behind the zone.

5. The system of claim 1 , wherein the positioning device comprises a plurality of light-emitting diodes directed to consecutive spots on the path the test tape travels.

6. The system of claim 1 , wherein the positioning device comprises at least one photosensor for scanning the test elements.

7. The system of claim 1 , wherein the positioning device is configured to detect a blank value in an unwetted area of the test field and a target value that is different therefrom in the wetted area.

8. The system of claim 1 , wherein the measuring device comprises a detector that is separate from the positioning device for detecting a signal that is representative of presence or concentration of an analyte in the sample liquid.

9. The system of claim 1 , wherein the test elements comprise flat test fields in the form of a reagent layer on the test tape, the test fields having a reference area for a blank value measurement.

10. The system of claim 1 , wherein the test tape comprises a line scale, marking holes or color marks and the positioning device comprises a scanner and a light barrier to scan the tape markings while the tape is advanced.

11. The system of claim 1 , wherein the wetted areas of the test elements have a diameter of less than 5 mm.

12. The system of claim 1 , wherein the measuring site is positioned 5 mm to 5 cm from the sample application site.

13. The system of claim 1 , further comprising a lancing device positioned at the sample application site for piercing a body part.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 23, 2015
From: ROCHE DIAGNOSTICS OPERATIONS, INC.
To: ROCHE DIABETES CARE, INC.
Reel/Frame 036008/0670 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 31, 2007
From: KRAMER, UWE; LIST, HANS
To: ROCHE DIAGNOSTICS GMBH
Reel/Frame 018828/0572 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 31, 2007
From: ROCHE DIAGNOSTICS GMBH
To: ROCHE DIAGNOSTICS OPERATIONS, INC.
Reel/Frame 018828/0617 →