Process for the preparation of coated polymer particles
View Patent ↗A process for the preparation of coated polymer particles containing superparamagnetic crystals, said process comprising reacting porous, surface-functionalized, superparamagnetic crystal-containing polymer particles of diameter 0.5 to 1.8 μm with at least one polyisocyanate and at least one diol or at least one epoxide.
1. A process for the preparation of coated polymer particles containing superparamagnetic crystals, the process comprising reacting porous, surface-functionalized, superparamagnetic crystal-containing polymer particles of diameter 0.5 to 1.8 μm with at least two epoxide compounds, at least one of which having an unsaturated carbon-carbon bond copolymerizable with an acrylic monomer; and reacting the formed particles with an acrylic monomer.
2. The process of claim 1 , wherein the acrylic monomer is acrylic acid.
3. The process of claim 1 , wherein the acrylic monomer is acrylamide.
4. The process of claim 1 , wherein the acrylic monomer is reacted with N-hydroxysuccinimide or with streptavidin.
5. The process of claim 1 , wherein at least one of the at least two epoxide compounds is a bisepoxide compound.
6. The process of claim 1 , wherein the at least two epoxide compounds are selected from the group consisting of glycidol and 1,4-bis-(2,3-epoxypropoxy)butane.
7. The process of claim 1 , wherein the at least two epoxide compounds are selected from the group consisting of 1,4-bis-(2,3-epoxypropoxy)butane and 2,2-bis(4-(2,3-epoxypropoxy)phenyl)-propane.
8. The process of claim 1 , wherein the at least two epoxide compounds are selected from the group consisting of glycidol, allylglycidyl ether and 1,4-bis-(2,3-epoxypropoxy)butane.
9. The process of claim 1 , wherein one of the at least two epoxide compounds has a molecular weight of 150 g/mol to 1000 g/mol.