IP Library Granted Patent US 7,838,040
Granted Patent B2
US 7,838,040 · App. 11/564,012 · Granted Nov 23, 2010

Method for regenerating cartilage

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Quick Facts
Patent No.
US 7,838,040
App. No.
11/564,012
Granted
Nov 23, 2010
Kind
B2
Abstract

Disclosed is a method for regenerating articular cartilage in an animal comprising administering a therapeutically effective amount of a non-demineralized particulate articular cartilage having a distribution of particle sizes within the range of from about 60 microns to about 500 microns.

Claims (13)

1. A method for regenerating articular cartilage in an animal having an articular cartilage defect, the method consisting of administering to the defect a therapeutically effective amount of a cartilage, consisting of non-demineralized particulate articular cartilage having a distribution of particle sizes within the range of from about 60 microns to about 500 microns, wherein the cartilage defect is densely packed and compacted with said cartilage to enhance regeneration of the articular cartilage within the defect.

2. A method for regenerating articular cartilage in an animal having an articular cartilage defect, the method consisting of (a) administering to the defect a therapeutically effective amount of a cartilage, said cartilage consisting of non-demineralized particulate articular cartilage having a distribution of particle sizes within the range of from about 60 microns to about 500 microns and (b) administering one or more additional cartilage growth promoting factors to the articular cartilage defect, wherein the cartilage defect is densely packed and compacted with said cartilage to enhance regeneration of the articular cartilage within the defect.

3. The method of claim 1 , wherein the animal is a human.

4. The method of claim 1 , wherein the non-demineralized particulate articular cartilage has a distribution of particulate sizes within the range of about 60 microns to about 250 microns.

5. The method of claim 1 , wherein the articular cartilage is hyaline cartilage.

6. The method of claim 2 , wherein the animal is a human.

7. The method of claim 2 , wherein the non-demineralized particulate articular cartilage has a distribution of particulate sizes within the range of about 60 microns to about 250 microns.

8. The method of claim 2 , wherein the articular cartilage is hyaline cartilage.

9. A method for regenerating articular cartilage in an animal having an articular cartilage defect, the method comprising administering to the defect a therapeutically effective amount of a cartilage, said cartilage consisting of non-demineralized particulate articular cartilage having a distribution of particle sizes within the range of from about 60 microns to about 500 microns, wherein the cartilage defect is densely packed and compacted with said cartilage to enhance regeneration of the articular cartilage within the defect.

10. The method of claim 9 , further comprising administering one or more additional cartilage growth promoting factors to the articular cartilage defect.

11. The method of claim 9 , wherein the animal is a human.

12. The method of claim 9 , wherein the non-demineralized particulate articular cartilage has a distribution of particulate sizes within the range of about 60 microns to about 250 microns.

13. The method of claim 9 , wherein the articular cartilage is hyaline cartilage.

Assignments (10)
RELEASE OF SECURITY INTEREST Recorded Aug 29, 2022
From: BANKUNITED, N.A.
To: VIVEX BIOLOGICS GROUP, INC.
Reel/Frame 061333/0853 →
SECURITY INTEREST Recorded Aug 4, 2022
From: VIVEX BIOLOGICS GROUP, INC.
To: HERITAGE BANK OF COMMERCE
Reel/Frame 061084/0607 →
RELEASE OF SECURITY INTEREST Recorded Dec 12, 2019
From: HERITAGE BANK OF COMMERCE
To: VIVEX BIOMEDICAL, INC.; UMTB BIOMEDICAL, INC; ADVANCED NUMED TECHNOLOGIES, LTD.; VIVEX BIOMEDICAL INTERNATIONAL, INC.
Reel/Frame 051282/0653 →
NOTICE OF GRANT OF SECURITY INTEREST IN PATENTS Recorded Dec 11, 2019
From: VIVEX BIOLOGICS GROUP, INC.
To: BANKUNITED, N.A.
Reel/Frame 051260/0064 →
CHANGE OF NAME Recorded Aug 19, 2019
From: VIVEX BIOMEDICAL, INC.
To: VIVEX BIOLOGICS, INC.
Reel/Frame 050085/0759 →
CHANGE OF NAME Recorded Aug 19, 2019
From: VIVEX BIOLOGICS, INC.
To: VIVEX BIOLOGICS GROUP, INC.
Reel/Frame 050085/0818 →
SECURITY INTEREST Recorded Feb 22, 2017
From: VIVEX BIOMEDICAL, INC.; UMTB BIOMEDICAL, INC.; ADVANCED NUMED TECHNOLOGIES, LTD.; VIVEX BIOMEDICAL INTERNATIONAL, INC.
To: HERITAGE BANK OF COMMERCE
Reel/Frame 041782/0452 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 6, 2017
From: UMTB ACQUISITION COMPANY, INC.
To: VIVEX BIOMEDICAL, INC.
Reel/Frame 041178/0317 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 1, 2014
From: UNIVERSITY OF MIAMI
To: UMTB ACQUISITION COMPANY, INC.
Reel/Frame 034288/0490 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 17, 2012
From: MALININ, THEODORE
To: UNIVERSITY OF MIAMI
Reel/Frame 028223/0011 →