Pharmaceutical Composition in the Form of a Water Soluble Solid Dosage Form

1 . A pharmaceutical composition comprising an active pharmaceutical composition and a water-soluble polymeric composition, the resultant mixture being formed into a solid, water-soluble dosage form.

2 . A pharmaceutical composition as claimed in claim 1 in which the melting point of the polymeric composition is lower than the melting point of the pharmaceutical composition.

3 . A pharmaceutical composition as claimed in claim 1 or claim 2 in which the polymeric composition is a polyethylene glycol.

4 . A pharmaceutical composition as claimed in claim 3 in which the polyethylene glycol has a molecular weight selected such that it is a solid at room temperature.

5 . A pharmaceutical composition as claimed in claim 3 or claim 4 in which the polyethylene glycol is present in the range 10 to 75 % m/m.

6 . A pharmaceutical composition as claimed in any one of the preceding claims in which the active pharmaceutical composition is a pesticide

7 . A pharmaceutical composition as claimed in claim 6 in which the pesticide is a herbicide.

8 . A pharmaceutical composition as claimed in claim 6 in which the pesticide is suitable for controlling or eradicating mammalian pests.

9 . A pharmaceutical composition as claimed in claim 8 in which the pesticide is suitable for controlling or eradicating ectoparasites.

10 . A pharmaceutical composition as claimed in claim 8 in which the pesticide is an acaricide.

11 . A pharmaceutical composition as claimed in claim 10 in which the acaricide belongs to the amidine group of pesticides.

12 . A pharmaceutical composition as claimed in claim 11 in which the pesticide is AMITRAZ.

13 . A pharmaceutical composition as claimed in claim 12 in which the AMITRAZ is present in the range 20 to 60 % m/m.

14 . A pharmaceutical composition as claimed in any one of the preceding claims which further includes any one or more of at least one dispersant, at least one disintegrant, at least one surfactant and at least one filler.

15 . A pharmaceutical composition as claimed in claim 14 in which the dispersant is a sodium salt of the condensation product of naphalene sulphuric acid.

16 . A pharmaceutical composition as claimed in claim 15 in which the dispersant is WETTOL D2.

17 . A pharmaceutical composition as claimed in any one of claims 14 to 16 in which the dispersant is present in the range 0.6 to 2 % m/m.

18 . A pharmaceutical composition as claimed in any one of claims 14 to 17 in which the surfactant is a non-ionic surfactant belonging to the nonylphenol ethoxylate group.

19 . A pharmaceutical composition as claimed in claim 18 in which the surfactant is ARKOPAL N090.

20 . A pharmaceutical composition as claimed in any one of claims 14 to 19 in which the dispersant is present in the range 1 to 4 % m/m.

21 . A pharmaceutical composition as claimed in any one of claims 14 to 20 in which the disintegrant is sodium starch glycolate.

22 . A pharmaceutical composition as claimed in any one of claims 14 to 21 which includes calcium carbonate present in the range 5 to 17 % m/m.

23 . A method of manufacturing a pharmaceutical composition in solid dosage form which includes melting a water-soluble polymeric composition, adding an active pharmaceutical composition and casting the resultant mixture into moulds.

24 . A method as claimed in claim 23 which further includes adding any one or more of at least one dispersant, at least one disintegrant, and at least one surfactant to the melted polymeric composition.

25 . A method as claimed in claim 23 or claim 24 in which the active pharmaceutical composition is a pesticide.

26 . A method as claimed in claim 25 in which the pesticide is a herbicide.

27 . A method as claimed in claim 25 in which the pesticide is suitable for controlling or eradicating mammalian pests.

28 . A method as claimed in claim 27 in which the pesticide is suitable for controlling or eradicating ectoparasites.

29 . A method as claimed in claim 27 in which the pesticide is an acaricide.

30 . A method as claimed in claim 29 in which the acaricide belongs to the amidine group of pesticides.

31 . A method as claimed in claim 30 in which the pesticide is AMITRAZ.