IP Library › Patent Application 11577176

Patent Application Utility PCT National Stage Small

App. No. 11/577,176 · Confirmation No. 1452

Compounds for Nonsense Suppression, Use of These Compounds for the Manufacture of a Medicament for Treating Somatic Mutation-Related Diseases

Inventors: Richard Wilde, Ellen Welch, Gary M. Karp

Abandoned -- Failure to Respond to an Office Action View Publication ↗

	Code	Description	Pages	PDF
2017-08-22	`ABN`	Abandonment	2	View
2016-12-29	`CTNF`	Non-Final Rejection	10	View
2016-12-29	`892`	List of references cited by examiner	1	View
2016-12-29	`SRNT`	Examiner's search strategy and results	180	View
2016-12-29	`SRNT`	Examiner's search strategy and results	1	View
2016-12-29	`SRFW`	Search information including classification, databases and other search related notes	2	View
2016-11-30	`WFEE`	Fee Worksheet (SB06)	1	View
2016-11-30	`RCEX`	Request for Continued Examination (RCE)	1	View
2016-11-30	`XT/`	Extension of Time	1	View
2016-11-30	`WFEE`	Fee Worksheet (SB06)	2	View
2016-11-30	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2016-11-18	`CTAV`	Advisory Action (PTOL-303)	3	View
2016-11-18	`A.NE.AFCP.D`	After Final Consideration Program Decision	1	View
2016-11-18	`AMSB`	Amendment Submitted/Entered with Filing of Continued Prosecution Application (CPA)/Request for Continued Examination(RCE)	1	View
2016-11-01	`AMSB`	Amendment Submitted/Entered with Filing of Continued Prosecution Application (CPA)/Request for Continued Examination(RCE)	1	View
2016-11-01	`CLM`	Claims	27	View
2016-11-01	`REM`	Applicant Arguments/Remarks Made in an Amendment	9	View
2016-11-01	`A.NE.AFCP`	After Final Consideration Program Request	1	View
2016-11-01	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2016-11-01	`WFEE`	Fee Worksheet (SB06)	1	View
2016-08-03	`CTFR`	Final Rejection	10	View
2016-08-03	`892`	List of references cited by examiner	1	View
2016-08-03	`1449`	List of References cited by applicant and considered by examiner	6	View
2016-08-03	`SRNT`	Examiner's search strategy and results	184	View
2016-08-03	`SRNT`	Examiner's search strategy and results	1	View
2016-08-03	`SRFW`	Search information including classification, databases and other search related notes	2	View
2016-06-28	`IDS`	Information Disclosure Statement (IDS) Form (SB08)	6	View
2016-06-28	`WFEE`	Fee Worksheet (SB06)	2	View
2016-06-28	`N417`	Electronic Filing System Acknowledgment Receipt	8	View
2016-06-28	`TRAN.LET`	Transmittal Letter	2	View
2016-06-24	`A...`	Amendment/Request for Reconsideration-After Non-Final Rejection	1	View
2016-06-24	`CLM`	Claims	26	View
2016-06-24	`REM`	Applicant Arguments/Remarks Made in an Amendment	4	View
2016-06-24	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2016-06-24	`WFEE`	Fee Worksheet (SB06)	1	View
2016-03-24	`CTNF`	Non-Final Rejection	9	View
2016-03-24	`892`	List of references cited by examiner	1	View
2016-03-24	`SRNT`	Examiner's search strategy and results	1	View
2016-03-24	`SRFW`	Search information including classification, databases and other search related notes	2	View
2016-03-15	`RFN.REQ`	Refund Request	3	View
2016-03-15	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2016-03-15	`IRFND`	Processed Request for Refund	3	View
2016-03-14	`RCEX`	Request for Continued Examination (RCE)	1	View
2016-03-14	`WFEE`	Fee Worksheet (SB06)	2	View
2016-03-14	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2016-03-14	`WFEE`	Fee Worksheet (SB06)	1	View
2016-03-02	`CTAV`	Advisory Action (PTOL-303)	3	View
2016-03-02	`ANE.I`	Amendment After Final or under 37CFR 1.312, initialed by the examiner.	1	View
2016-02-16	`AMSB`	Amendment Submitted/Entered with Filing of Continued Prosecution Application (CPA)/Request for Continued Examination(RCE)	1	View
2016-02-16	`CLM`	Claims	26	View
2016-02-16	`REM`	Applicant Arguments/Remarks Made in an Amendment	3	View
2016-02-16	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2016-02-16	`WFEE`	Fee Worksheet (SB06)	1	View
2015-12-15	`CTFR`	Final Rejection	9	View
2015-12-15	`892`	List of references cited by examiner	1	View
2015-12-15	`SRNT`	Examiner's search strategy and results	77	View
2015-12-15	`SRNT`	Examiner's search strategy and results	1	View
2015-12-15	`SRFW`	Search information including classification, databases and other search related notes	2	View
2015-12-15	`SRNT`	Examiner's search strategy and results	36	View
2015-09-02	`A...`	Amendment/Request for Reconsideration-After Non-Final Rejection	1	View
2015-09-02	`CLM`	Claims	36	View
2015-09-02	`REM`	Applicant Arguments/Remarks Made in an Amendment	3	View
2015-09-02	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2015-09-02	`WFEE`	Fee Worksheet (SB06)	1	View
2015-06-02	`CTNF`	Non-Final Rejection	8	View
2015-06-02	`892`	List of references cited by examiner	1	View
2015-06-02	`SRNT`	Examiner's search strategy and results	33	View
2015-06-02	`SRFW`	Search information including classification, databases and other search related notes	2	View
2015-05-13	`RCEX`	Request for Continued Examination (RCE)	2	View
2015-05-13	`XT/`	Extension of Time	1	View
2015-05-13	`WFEE`	Fee Worksheet (SB06)	2	View
2015-05-13	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2015-05-13	`WFEE`	Fee Worksheet (SB06)	2	View
2015-05-13	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2015-05-13	`WFEE`	Fee Worksheet (SB06)	1	View
2015-04-15	`CTAV`	Advisory Action (PTOL-303)	3	View
2015-04-15	`AMSB`	Amendment Submitted/Entered with Filing of Continued Prosecution Application (CPA)/Request for Continued Examination(RCE)	1	View
2015-03-13	`A.NE`	Response After Final Action	1	View
2015-03-13	`CLM`	Claims	23	View
2015-03-13	`REM`	Applicant Arguments/Remarks Made in an Amendment	3	View
2015-03-13	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2015-03-13	`WFEE`	Fee Worksheet (SB06)	1	View
2015-01-13	`CTFR`	Final Rejection	8	View
2015-01-13	`892`	List of references cited by examiner	1	View
2015-01-13	`SRFW`	Search information including classification, databases and other search related notes	2	View
2015-01-13	`SRNT`	Examiner's search strategy and results	1	View
2014-12-29	`A.NQ`	Amendment Crossed in Mail	1	View
2014-12-29	`CLM`	Claims	22	View
2014-12-29	`REM`	Applicant Arguments/Remarks Made in an Amendment	2	View
2014-12-29	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2014-12-24	`A...`	Amendment/Request for Reconsideration-After Non-Final Rejection	1	View
2014-12-24	`CLM`	Claims	23	View
2014-12-24	`REM`	Applicant Arguments/Remarks Made in an Amendment	3	View
2014-12-24	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2014-12-24	`WFEE`	Fee Worksheet (SB06)	1	View
2014-12-24	`WFEE`	Fee Worksheet (SB06)	1	View
2014-09-29	`CTNF`	Non-Final Rejection	7	View
2014-09-29	`892`	List of references cited by examiner	1	View
2014-09-29	`1449`	List of References cited by applicant and considered by examiner	2	View
2014-09-29	`BIB`	Bibliographic Data Sheet	1	View
2014-09-29	`SRFW`	Search information including classification, databases and other search related notes	2	View
2014-07-18	`IDS`	Information Disclosure Statement (IDS) Form (SB08)	4	View
2014-07-18	`REF.OTHER`	Other reference-Patent/Application/Search Documents	4	View
2014-07-18	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2014-07-18	`TRAN.LET`	Transmittal Letter	2	View
2014-06-10	`RCEX`	Request for Continued Examination (RCE)	3	View
2014-06-10	`XT/`	Extension of Time	2	View
2014-06-10	`WFEE`	Fee Worksheet (SB06)	2	View
2014-06-10	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2014-05-20	`CTAV`	Advisory Action (PTOL-303)	3	View
2014-05-20	`ANE.I`	Amendment After Final or under 37CFR 1.312, initialed by the examiner.	1	View
2014-04-11	`AMSB`	Amendment Submitted/Entered with Filing of Continued Prosecution Application (CPA)/Request for Continued Examination(RCE)	1	View
2014-04-11	`CLM`	Claims	21	View
2014-04-11	`REM`	Applicant Arguments/Remarks Made in an Amendment	3	View
2014-04-11	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2014-04-11	`WFEE`	Fee Worksheet (SB06)	1	View
2014-02-11	`CTFR`	Final Rejection	7	View
2014-02-11	`892`	List of references cited by examiner	1	View
2014-02-11	`SRNT`	Examiner's search strategy and results	1	View
2014-02-11	`SRNT`	Examiner's search strategy and results	36	View
2014-02-11	`SRFW`	Search information including classification, databases and other search related notes	2	View
2014-01-02	`A...`	Amendment/Request for Reconsideration-After Non-Final Rejection	1	View
2014-01-02	`CLM`	Claims	20	View
2014-01-02	`REM`	Applicant Arguments/Remarks Made in an Amendment	3	View
2014-01-02	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2014-01-02	`WFEE`	Fee Worksheet (SB06)	1	View
2013-10-01	`CTNF`	Non-Final Rejection	6	View
2013-10-01	`892`	List of references cited by examiner	1	View
2013-10-01	`SRNT`	Examiner's search strategy and results	1	View
2013-10-01	`SRNT`	Examiner's search strategy and results	4	View
2013-10-01	`SRFW`	Search information including classification, databases and other search related notes	2	View
2011-05-27	`WFEE`	Fee Worksheet (SB06)	4	View
2011-05-24	`RFN.REQ`	Refund Request	3	View
2011-05-24	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2011-05-13	`RCEX`	Request for Continued Examination (RCE)	3	View
2011-05-13	`WFEE`	Fee Worksheet (SB06)	2	View
2011-05-13	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2011-04-20	`CTAV`	Advisory Action (PTOL-303)	3	View
2011-04-20	`AMSB`	Amendment Submitted/Entered with Filing of Continued Prosecution Application (CPA)/Request for Continued Examination(RCE)	1	View
2011-04-14	`A.NE`	Response After Final Action	1	View
2011-04-14	`REM`	Applicant Arguments/Remarks Made in an Amendment	2	View
2011-04-14	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2011-04-14	`WFEE`	Fee Worksheet (SB06)	1	View
2011-04-14	`CLM`	Claims	20	View
2011-02-14	`CTFR`	Final Rejection	7	View
2011-02-14	`892`	List of references cited by examiner	1	View
2011-02-14	`SRFW`	Search information including classification, databases and other search related notes	1	View
2011-02-14	`SRNT`	Examiner's search strategy and results	7	View
2011-02-14	`SRNT`	Examiner's search strategy and results	2	View
2010-11-17	`A...`	Amendment/Request for Reconsideration-After Non-Final Rejection	1	View
2010-11-17	`CLM`	Claims	20	View
2010-11-17	`REM`	Applicant Arguments/Remarks Made in an Amendment	5	View
2010-11-17	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2010-11-17	`WFEE`	Fee Worksheet (SB06)	1	View
2010-08-17	`CTNF`	Non-Final Rejection	13	View
2010-08-17	`892`	List of references cited by examiner	1	View
2010-08-17	`SRFW`	Search information including classification, databases and other search related notes	1	View
2010-08-17	`SRNT`	Examiner's search strategy and results	2	View
2010-08-17	`SRNT`	Examiner's search strategy and results	7	View
2010-03-22	`RCEX`	Request for Continued Examination (RCE)	3	View
2010-03-22	`AMSB`	Amendment Submitted/Entered with Filing of Continued Prosecution Application (CPA)/Request for Continued Examination(RCE)	1	View
2010-03-22	`REM`	Applicant Arguments/Remarks Made in an Amendment	14	View
2010-03-22	`XT/`	Extension of Time	2	View
2010-03-22	`WFEE`	Fee Worksheet (SB06)	2	View
2010-03-22	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2010-02-01	`CTAV`	Advisory Action (PTOL-303)	6	View
2010-02-01	`ANE.I`	Amendment After Final or under 37CFR 1.312, initialed by the examiner.	1	View
2010-02-01	`CTAV`	Advisory Action (PTOL-303)	1	View
2010-01-20	`A.NE`	Response After Final Action	1	View
2010-01-20	`REM`	Applicant Arguments/Remarks Made in an Amendment	5	View
2010-01-20	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2010-01-20	`WFEE`	Fee Worksheet (SB06)	1	View
2010-01-20	`CLM`	Claims	18	View
2009-11-20	`CTFR`	Final Rejection	10	View
2009-11-20	`SRFW`	Search information including classification, databases and other search related notes	1	View
2009-11-20	`SRNT`	Examiner's search strategy and results	1	View
2009-11-20	`SRNT`	Examiner's search strategy and results	17	View
2009-08-31	`A...`	Amendment/Request for Reconsideration-After Non-Final Rejection	1	View
2009-08-31	`CLM`	Claims	17	View
2009-08-31	`REM`	Applicant Arguments/Remarks Made in an Amendment	13	View
2009-08-31	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2009-08-31	`WFEE`	Fee Worksheet (SB06)	1	View
2009-05-29	`CTNF`	Non-Final Rejection	11	View
2009-05-29	`892`	List of references cited by examiner	1	View
2009-05-29	`SRFW`	Search information including classification, databases and other search related notes	1	View
2009-05-29	`BIB`	Bibliographic Data Sheet	1	View
2009-05-29	`SRNT`	Examiner's search strategy and results	1	View
2009-05-29	`1449`	List of References cited by applicant and considered by examiner	2	View
2009-05-29	`SRNT`	Examiner's search strategy and results	25	View
2009-05-04	`ELC.`	Response to Election / Restriction Filed	1	View
2009-05-04	`CLM`	Claims	18	View
2009-05-04	`REM`	Applicant Arguments/Remarks Made in an Amendment	2	View
2009-05-04	`WFEE`	Fee Worksheet (SB06)	2	View
2009-05-04	`N417`	Electronic Filing System Acknowledgment Receipt	3	View
2009-05-04	`XT/`	Extension of Time	2	View
2009-05-04	`WFEE`	Fee Worksheet (SB06)	1	View
2009-03-03	`CTRS`	Requirement for Restriction/Election	12	View
2009-03-03	`892`	List of references cited by examiner	1	View
2009-03-03	`FOR`	Foreign Reference	102	View
2008-10-30	`NTC.PUB`	Notice of Publication	1	View
2008-09-16	`TRAN.LET`	Transmittal Letter	2	View
2008-09-16	`IDS`	Information Disclosure Statement (IDS) Form (SB08)	2	View
2008-09-16	`TRAN.LET`	Transmittal Letter	2	View
2008-09-16	`FOR`	Foreign Reference	59	View
2008-09-16	`FOR`	Foreign Reference	49	View
2008-09-16	`FOR`	Foreign Reference	102	View
2008-09-16	`FOR`	Foreign Reference	64	View
2008-09-16	`N417`	Electronic Filing System Acknowledgment Receipt	3	View
2008-07-11	`M903`	Notice of Designated Office (DO) / Elected Office (EO) Acceptance Mailed	2	View
2008-07-11	`APP.FILE.REC`	Filing Receipt	3	View
2008-06-13	`PEFR`	Applicant Response to Pre-Exam Formalities Notice	5	View
2008-06-13	`OATH`	Oath or Declaration filed	4	View
2008-06-13	`XT/`	Extension of Time	2	View
2008-06-13	`LET.`	Miscellaneous Incoming Letter	2	View
2008-06-13	`WFEE`	Fee Worksheet (SB06)	2	View
2008-06-13	`N417`	Electronic Filing System Acknowledgment Receipt	3	View
2008-06-13	`PEFR`	Applicant Response to Pre-Exam Formalities Notice	5	View
2008-06-13	`OATH`	Oath or Declaration filed	4	View
2008-06-13	`XT/`	Extension of Time	2	View
2008-06-13	`LET.`	Miscellaneous Incoming Letter	2	View
2008-06-13	`ABST`	Abstract	1	View
2008-06-13	`WFEE`	Fee Worksheet (SB06)	1	View
2008-06-13	`IMIS`	Miscellaneous Internal Document	1	View
2008-06-13	`WFEE`	Fee Worksheet (SB06)	1	View
2008-02-15	`M905`	Notice of DO/EO Missing Requirements Mailed	2	View
2008-01-16	`A.PE`	Preliminary Amendment	1	View
2008-01-16	`SPEC`	Specification	1	View
2008-01-16	`REM`	Applicant Arguments/Remarks Made in an Amendment	1	View
2008-01-16	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2007-11-29	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2007-11-29	`PA..`	Power of Attorney	4	View
2007-04-12	`TRNA`	Transmittal of New Application	5	View
2007-04-12	`A.PE`	Preliminary Amendment	1	View
2007-04-12	`SPEC`	Specification	1	View
2007-04-12	`REM`	Applicant Arguments/Remarks Made in an Amendment	1	View
2007-04-12	`SPEC`	Specification	137	View
2007-04-12	`CLM`	Claims	22	View
2007-04-12	`ABST`	Abstract	1	View
2007-04-12	`DRW`	Drawings-only black and white line drawings	3	View
2007-04-12	`371P`	Documents submitted with 371 (National Stage) Applications	6	View
2007-04-12	`WFEE`	Fee Worksheet (SB06)	2	View
2007-04-12	`N417`	Electronic Filing System Acknowledgment Receipt	3	View
2007-04-12	`136A`	Authorization for Extension of Time all replies	5	View
2007-04-12	`ABST`	Abstract	1	View
2007-04-12	`SPEC`	Specification	137	View
2007-04-12	`CLM`	Claims	22	View
2007-04-12	`DRW`	Drawings-only black and white line drawings	3	View
2007-04-12	`ABST`	Abstract	1	View
2007-04-12	`FRPR`	Certified Copy of Foreign Priority Application	229	View
2007-04-12	`FRPR`	Certified Copy of Foreign Priority Application	148	View
2007-04-12	`FRPR`	Certified Copy of Foreign Priority Application	285	View
2007-04-12	`FRPR`	Certified Copy of Foreign Priority Application	128	View
2007-04-12	`FRPR`	Certified Copy of Foreign Priority Application	89	View
2007-04-12	`FRPR`	Certified Copy of Foreign Priority Application	286	View
2007-04-12	`ABST`	Abstract	1	View
2007-04-12	`WFEE`	Fee Worksheet (SB06)	1	View
2007-04-12	`WCLM`	Claims Worksheet (PTO-2022)	1	View
2007-04-12	`IMIS`	Miscellaneous Internal Document	1	View

Inventors

Richard Wilde Somerville, NJ

Ellen Welch Califon, NJ

Gary M. Karp Princeton Junction, NJ

Attorneys & Agents of Record

DANIEL SCOLA Reg. 29855 Attorney · HOFFMANN & BARON, LLP

GLENN HENNEBERGER Reg. 36074 Attorney · HOFFMANN AND BARON, LLP

STEVEN ZUSCHLAG Reg. 43309 Agent · HOFFMANN & BARON, LLP

JOHN GALLAGHER Reg. 35516 Attorney · HOFFMANN & BARON LLP

JOSEPH RICIGLIANO Reg. 48511 Attorney · HOFFMANN & BARON, LLP

LAUREN EMR Reg. 46139 Agent · HOFFMANN & BARON, LLP

SUSAN SIPOS Reg. 43128 Attorney · HOFFMANN AND BARON, LLP

KEVIN MCDERMOTT Reg. 35946 Attorney · HOFFMANN AND BARON, LLP

SALVATORE ABBRUZZESE Reg. 30152 Attorney · HOFFMAN & BARON LLP

JOHN SOPKO Reg. 41321 Attorney · HOFFMANN & BARON, LLP

CHRISTINE DIETZEL Reg. 37309 Agent · KLAUBER AND JACKSON LLC

KAREN KING Reg. 41898 Attorney · HOFFMAN & BARON, LLP

RONALD BARON Reg. 29281 Attorney · HOFFMANN & BARON LLP

LINDA CHIN Reg. 58205 Attorney · HOFFMANN & BARON, LLP

ANDREA WILKOVICH Reg. 53773 Attorney · HOFFMANN & BARON, LLP

ALEXANDRIA STITELER Reg. 80707 Agent

MICHAEL CHAKANSKY Reg. 31600 Attorney · HOFFMAN & BARON, LLP

ALEXANDER VODOVOZOV Reg. 55701 Attorney · HOFFMANN & BARON, LLP

JAMES HARRINGTON Reg. 44741 Attorney · HOFFMAN AND BARON LLP

ANTHONY BENNETT Reg. 40910 Attorney · HOFFMANN AND BARON, LLP

Classification

USPC 514/312

C07D271/06 C07D231/12 C07D233/64 C07D249/08 C07D251/24 C07D261/08 C07D263/32 C07D271/10 C07D271/107 C07D277/30 C07D285/12 C07D307/68 C07D333/24 C07D401/04 C07D403/04 C07D405/04 C07D409/04 C07D413/04 C07D413/06 C07D413/12 C07D417/04 C07F9/65306

Prosecution

Examiner: RICCI, CRAIG D
Art Unit: 1628
Customer No.: 23869
Docket No.: 1368-22 PCT E/US/RCE VI
Confirmation No.: 1452

Publication

Pub. No.: US20080269191A1
Pub. Date: 2008-10-30

Parent PCT is a National Stage Entry of

→

PCT/US2005/036762

Filed 2005-10-13 · Abandoned -- Failure to Respond to an Office Action

Parent Claims priority from a provisional application

→

App. 60/617,670

Filed 2004-10-13 · Provisional Application Expired

Parent Claims priority from a provisional application

→

App. 60/617,633

Filed 2004-10-13 · Provisional Application Expired

Parent Claims priority from a provisional application

→

App. 60/617,655

Filed 2004-10-13 · Provisional Application Expired

Parent Claims priority from a provisional application

→

App. 60/617,634

Filed 2004-10-13 · Provisional Application Expired

Parent Claims priority from a provisional application

→

App. 60/617,653

Filed 2004-10-13 · Provisional Application Expired

Parent Claims priority from a provisional application

→

App. 60/624,170

Filed 2004-11-03 · Provisional Application Expired

PTC THERAPEUTICS, INC.

from MIDCAP FINANCIAL TRUST, AS AGENT

RELEASE OF SECURITY INTEREST Recorded 2020-07-14

053209/0872 →

MIDCAP FINANCIAL TRUST, AS AGENT

from PTC THERAPEUTICS, INC.

CORRECTIVE ASSIGNMENT TO CORRECT THE INCLUSION OF 6420591,6583309,6503713, 5843995,7029846,7056656, 6468969,6486305,6630294, 6989256,6627398,8247167, 9017935 PREVIOUSLY RECORDED ON REEL 042418 FRAME 0774. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY INTEREST. Recorded 2017-08-24

043672/0096 →

MIDCAP FINANCIAL TRUST, AS AGENT

from PTC THERAPEUTICS, INC.

SECURITY INTEREST Recorded 2017-05-08

042418/0774 →

PTC THERAPEUTICS, INC.

from KARP, GARY M., WELCH, ELLEN, WILDE, RICHARD

ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded 2007-10-17

019973/0021 →

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