1,3,4-oxadiazole benzoic acid compounds and their use for nonsense suppression and the treatment of disease

1. A compound of Formula 1-A:

wherein:

R 3 is absent;

W is selected from the group consisting of:

wherein when W is selected from the group consisting of:

then

 shown in Formula 1-A is in the meta or para position; and

wherein when W is selected from the group consisting of

then

 shown in Formula 1-A is in the meta position;

and a pharmaceutically acceptable salt of said compound of Formula 1-A, wherein * indicates the only bond of attachment for W, and wherein said bond of attachment is a direct bond of attachment.

2. A compound selected from the group consisting of:

and a pharmaceutically acceptable salt thereof.

3. The compound of claim 2 , wherein said compound is selected from the group consisting of:

and a pharmaceutically acceptable salt thereof.