IP Library › Granted Patent US 7,641,902
Granted Patent B2
US 7,641,902 · App. 11/601,895 · Granted Jan 5, 2010

Compositions and methods for detecting cancer and for inhibiting metastasis

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Quick Facts
Patent No.
US 7,641,902
App. No.
11/601,895
Granted
Jan 5, 2010
Kind
B2
Abstract

The present invention relates to compositions and methods for detecting cancer (e.g., prostate cancer) and for inhibiting metastasis (e.g., associated with prostate cancer). In particular, the present invention provides methods of detecting vimentin expression and secretion and for characterizing cancer (e.g., prostate cancer). In addition, the present invention provides methods for inhibiting metastasis (e.g., of prostate cancer) via altering (e.g., inhibiting) vimentin expression and/or activity.

Claims (5)

1. A method of inhibiting prostate cancer metastasis in a subject comprising administering an anti-vimentin antibody to a subject having prostate cancer metastasis to bone.

2. The method of claim 1 , wherein said antibody is a polyclonal antibody.

3. The method of claim 1 , wherein said antibody is a monoclonal antibody.

4. The method of claim 1 , wherein said antibody is a humanized antibody.

5. The method of claim 1 , wherein said antibody is conjugated to a cytotoxic agent.