Cross-flow filter cassette
View Patent ↗An improved cross-flow filtration unit utilizing at least one two-ply membrane is disclosed that has a particular pore size relationship in the two membrane layers.
1. A cross-flow filtration cassette having a feed inlet and feed flow channel; a permeate flow channel and a permeate outlet; a retentate outlet; and at least one two-ply microporous separation membrane having a front side ply facing said feed channel and a back side ply facing said permeate channel wherein said plies physically lie on top of one another and are joined at their peripheries by spacers but are not bonded together in the area between said spacers, wherein the flow of liquid feed through said separation membrane is tangential over the surface of said separation membrane and the flow of permeate through said separation membrane is from the front side ply to the back side ply, and wherein the pores of said separation membrane are sized such that the average pore size of said front side ply is from about 1.4 to about 5 times the average pore size of said back side ply.
2. The filtration cassette of claim 1 with a single two-ply separation membrane.
3. The filtration cassette of claim 1 containing a plurality of said two-ply separation membranes.
4. The filtration cassette of claim 3 containing at least one sequence of channels and two-ply membrane in the following order: feed channel, two-ply membrane, permeate channel, two-ply membrane.
5. The filtration cassette of any of claims 1 - 4 wherein the average pore size of said back side ply is such as to impart to said back side ply a molecular weight cutoff of at least 1000 Daltons.
6. The filtration cassette of claim 5 wherein the maximum average pore size of said back side ply is 1.2 microns.
7. The filtration cassette of any of claims 1 - 4 wherein the average pore size of said back side ply is from 0.2 to 1.2 microns.