Dietary supplement enhancing the muscular energy metabolism, comprising an alkanoyl carnitine and ribose
A health food/dietary supplement is disclosed suitable for enhancing muscular energy metabolism, comprising as its characterizing active ingredits an alkanoyl L-carnitine and ribose.
1 . A food/dietary supplement in the form of tablets, capsules, lozenges, pills, granulates, creams, syrups or drops which comprises the following characterizing ingredients:
(a) an alkanoyl L-carnitine selected from the group consisting of isovaleryl L-carnitine, and propionyl L-carnitine or the pharmacologically acceptable salts thereof or mixtures thereof; and
(b) ribose or a phosphorylate derivative thereof
wherein the weight ratio of ingredients (a):(b) ranges from 1:1 to 1:10.
2 . The supplement of claim 1 which further comprises vitamins, sugars, coenzymes, mineral substances, aminoacids, peptides and antioxidants.
3 . The supplement of claim 2 wherein the pharmacologically acceptable salt is selected from the group consisting of chloride; bromide; iodide; aspartate, acid aspartate; citrate, acid citrate; tartrate; phosphate, acid phosphate; fumarate, acid fumarate; glycerophosphate; glucose phosphate; lactate; maleate, acid maleate; mucate; orotate; oxalate; acid oxalate; sulphate, acid sulphate; trichloroacetate; trifluoroacetate and methane sulphonate.
4 . A food/dietary supplement in the form of tablets, capsules, lozenges, pills, granulates, creams, syrups or drops which comprises the following characterizing ingredients:
(a) an alkanoyl L-carnitine selected from the group consisting of isovaleryl L-carnitine, and propionyl L-carnitine or the pharmacologically acceptable salts thereof or mixtures thereof;
(b) ribose or a phosphorylate derivative thereof, and
(c) a carnitine selected from the group comprising L-carnitine, acetyl L-carnitine, butyryl L-carnitine and valeryl L-carnitine or the pharmacologically acceptable salts or mixtures thereof;
wherein the weight ratio of ingredients (a):(b):(c) ranges from 1:1 to 1:10:2.
5 . The supplement of claim 4 which further comprises vitamins, sugars, coenzymes, mineral substances, aminoacids, peptides and antioxidants.
6 . The supplement of claim 4 wherein the pharmacologically acceptable salt is selected from the group consisting of chloride; bromide; iodide; aspartate, acid aspartate; citrate, acid citrate; tartrate; phosphate, acid phosphate; fumarate, acid fumarate; glycerophosphate; glucose phosphate; lactate; maleate, acid maleate; mucate; orotate; oxalate; acid oxalate; sulphate, acid sulphate; trichloroacetate; trifluoroacetate and methane sulphonate.
7 . The supplement of claim 4 , in unit dosage form, comprising:
Propionyl L-carnitine
125 mg
Acetyl L-carnitine
125 mg
L-carnitine
125 mg
Isovaleryl L-carnitine
125 mg
Ribose
500 mg
8 . The supplement of claim 4 , in unit dosage form, comprising:
Propionyl L-carnitine
250
mg
Acetyl L-carnitine
250
mg
Isovaleryl L-carnitine
250
mg
L-carnitine
250
mg
Ribose
2
g
Ribonucleic acid
100
mg
Deoxyribonucleic acid
100
mg
9 . The supplement of claim 4 , in unit dosage form, comprising:
Propionyl L-carnitine
250
mg
Acetyl L-carnitine
250
mg
Isovaleryl L-carnitine
250
mg
L-carnitine
250
mg
Ribose
2
g
L-glutamine
100
mg
L-alanine
100
mg
L-arginine
100
mg
L-glicine
100
mg
L-histidine
100
mg
L-isoleucine
100
mg
L-phenylalanine
50
mg
L-threonine
50
mg
L-serine
100
mg
10 . The supplement of claim 4 , in unit dosage form, comprising:
Propionyl L-carnitine
250
mg
Acetyl L-carnitine
250
mg
Isovaleryl L-carnitine
250
mg
L-carnitine
250
mg
Ribose
1
g
Glucose-1,6-diphosphate
200
mg
Fructose-1,6-diphosphate
200
mg
Galactose-1,6-phosphate
200
mg
Glycerol-3-phosphate
200
mg
Phosphenylpyruvate
100
mg
Thiamine pyrophosphate
5
mg
Pyridoxal-5-phosphate
5
mg
Magnesium stearate
2
mg
11 . The supplement of claim 4 , in unit dosage form, comprising:
Propionyl L-carnitine
250
mg
Acetil L-carnitine
250
mg
Isovaleryl L-carnitine
250
mg
L-carnitine
250
mg
Ribose
1
g
Vit. A
1250
U.I.
Vit. B 1
0.5
mg
Vit. B 6
30
mg
Vit. C
50
mg
Vit. E
5
mg
Nicotinamide
25
mg
Vit. B 12
100
mcg
Vit. D
100
U.I.
Pantothenic acid
30
mg
Magnesium glycinate
5
mg
Manganese
1
mg
L-Selenomethionine
50
mcg
Molybdenum
10
mcg
Zinc
1
mg
12 . A method for the treatment of states of myocardial or skeletal muscle anoxia occurring in coronary or post-infarct disorders or during prolonged physical activity and muscle fatigue, which comprises administering to an individual in need thereof a combination composition comprising the following ingredients:
(a) an alkanoyl L-carnitine selected from the group consisting of isovaleryl L-carnitine, propionyl L-carnitine or the pharmacologically acceptable salts thereof or mixtures thereof, and
(b) ribose or a phosphorylate derivative thereof.
13 . A method for the treatment of states of myocardial or skeletal muscle dysfunction related to conditions of anoxia or insufficient energy supply as occurring in coronary or post-infarct disorders or during prolonged physical activity and muscle fatigue, which comprises administering to an individual in need thereof a combination composition comprising the following ingredients:
(a) an alkanoyl L-carnitine selected from the group consisting of isovaleryl L-carnitine, propionyl L-carnitine or the pharmacologically acceptable salts thereof or mixtures thereof, and
(b) ribose or a phosphorylate derivative thereof.
14 . A method for the treatment of states of myocardial or skeletal muscle anoxia occurring in coronary or post-infarct disorders or during prolonged physical activity and muscle fatigue, which comprises administering to an individual in need thereof a combination composition comprising the following ingredients:
(a) an alkanoyl L-carnitine selected from the group consisting of isovaleryl L-carnitine, propionyl L-carnitine or the pharmacologically acceptable salts thereof or mixtures thereof,
(b) ribose or a phosphorylate derivative thereof, and
(c) a carnitine selected from the group comprising L-carnitine, acetyl L-carnitine, butyryl L-carnitine and valeryl L-carnitine or the pharmacologically acceptable salts or mixtures thereof.
15 . A method for the treatment of states of myocardial or skeletal muscle dysfunction related to conditions of anoxia or insufficient energy supply as occurring in coronary or post-infarct disorders or during prolonged physical activity and muscle fatigue, which comprises administering to an individual in need thereof a combination composition comprising the following ingredients:
(a) an alkanoyl L-carnitine selected from the group consisting of isovaleryl L-carnitine, propionyl L-carnitine or the pharmacologically acceptable salts thereof or mixtures thereof,
(b) ribose or a phosphorylate derivative thereof, and
(c) a carnitine selected from the group comprising L-carnitine, acetyl L-carnitine, butyryl L-carnitine and valeryl L-carnitine or the pharmacologically acceptable salts or mixtures thereof.