Device system and method for tissue displacement or separation
A tissue displacement/separation device is provided. The device includes a bladder which is expandable between a first tissue and a second tissue of a body. The bladder has an expanded shape which is selected capable of displacing or separating the first tissue from the second tissue in a manner suitable for protecting the first tissue from an effect of a treatment applied to the second tissue.
1. A method of forming a seamless bladder comprising:
(a) providing a volumetric bladder template produced from material soluble in a first liquid;
(b) coating said template with a solution of a polymer insoluble in said first liquid to thereby generate a polymeric coat on said template; and
(c) exposing said template and polymeric coat to said first liquid thereby dissolving said template and leaving said polymeric coat to form the seamless bladder.
2. The method of claim 1 , wherein said first liquid is a hydrophilic liquid.
3. The method of claim 1 , wherein said material soluble in a first liquid is gelatin or agar.
4. The method of claim 1 , wherein said polymer is selected from the group consisting of a poly(alkanoic acid), a polyorhtoester, a polyphosphazene, a polyphosphate ester and a polyanhydride.
5. The method of claim 4 , wherein said poly(alkanoic acid) is selected from the group consisting of poly(lactic acid), poly(lactic acid-glycolic acid) and poly(lactic acid-caprolactone).
6. The method of claim 1 , wherein coating comprises coating by dipping said template in said first liquid.
7. The method of claim 6 , comprising repeating said dipping until a desired thickness is achieved.
8. The method of claim 6 , wherein dipping comprises dipping at a constant speed.
9. The method of claim 1 , wherein coating comprises coating said template from all sides except for a port region of said bladder.
10. The method of claim 9 , comprising forcefully sticking a biodegradable plug into said port.
11. The method of claim 9 , comprising removing said dissolved template via said port.
12. The method of claim 1 , wherein said bladder is formed to have a port with a diameter of between 1/100 and ⅕ of a diameter of said bladder.
13. The method of claim 1 , wherein providing a volumetric bladder template comprises forming a bladder template using a mold.
14. The method of claim 1 , wherein said polymer is selected to biodegrade when inside a body over a period of weeks to months.