IP Library Granted Patent US 8,206,753
Granted Patent B2
US 8,206,753 · App. 11/635,305 · Granted Jun 26, 2012

Anti-inflammatory botanical products for the treatment of metabolic syndrome and diabetes

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Quick Facts
Patent No.
US 8,206,753
App. No.
11/635,305
Granted
Jun 26, 2012
Kind
B2
Abstract

Disclosed are botanically based compositions and methods useful for the treatment of metabolic syndrome and diabetes type 2. Compositions, kits, and methods are additionally disclosed for means to augment the activity of identified glucose and insulin regulating drugs.

Claims (4)

1. An oral composition for treating an insulin related disorder in a subject in need thereof, said composition consisting essentially of a therapeutically effective amount of a compound selected from the group consisting of tetrahydro-isohumulone, tetrahydro-isocohumulone, and tetrahydro-isoadhumulone; and metformin, wherein the composition is in a dosage form for oral administration.

2. An oral composition for treating diabetes in a subject in need thereof, said composition consisting essentially of a therapeutically effective amount of a compound selected from the group consisting of tetrahydro-isohumulone, tetrahydro-isocohumulone, and tetrahydro-isoadhumulone; and metformin, wherein the composition is in a dosage form for oral administration.

3. An oral composition for treating obesity in a subject in need thereof, said composition consisting essentially of a therapeutically effective amount of a compound selected from the group consisting of tetrahydro-isohumulone, tetrahydro-isocohumulone, and tetrahydro-isoadhumulone; and metformin, wherein the composition is in a dosage form for oral administration.

4. An oral composition for treating a cardiovascular disease in a subject in need thereof, said composition consisting essentially of a therapeutically effective amount of a compound selected from the group consisting of tetrahydro-isohumulone, tetrahydro-isocohumulone, and tetrahydro-isoadhumulone; and metformin, wherein the composition is in a dosage form for oral administration.

Assignments (6)
TERMINATION AND RELEASE OF PATENT SECURITY AGREEMENT - REEL/FRAME 057981/0156 Recorded Dec 24, 2025
From: FORTRESS CREDIT CORP.
To: METAGENICS LLC (FKA METAGENICS, INC.); METAPROTEOMICS, LLC
Reel/Frame 074057/0392 →
TERMINATION AND RELEASE OF PATENT SECURITY AGREEMENT - REEL/FRAME 058015/0602 Recorded Dec 23, 2025
From: FORTRESS CREDIT CORP.
To: METAGENICS LLC (FKA METAGENICS, INC.); METAPROTEOMICS, LLC
Reel/Frame 074050/0670 →
SECURITY INTEREST Recorded Nov 4, 2021
From: METAGENICS, INC.; METAPROTEOMICS, LLC
To: FORTRESS CREDIT CORP. (AS COLLATERAL AGENT)
Reel/Frame 058015/0602 →
SECURITY INTEREST Recorded Nov 1, 2021
From: METAGENICS, INC.; METAPROTEOMICS, LLC
To: FORTRESS CREDIT CORP., AS COLLATERAL AGENT
Reel/Frame 057981/0156 →
RELEASE OF SECURITY INTEREST Recorded Oct 25, 2021
From: BANK OF AMERICA, N.A.
To: META PROTEOMICS, LLC
Reel/Frame 057909/0199 →
SECURITY AGREEMENT Recorded Oct 15, 2009
From: META PROTEOMICS, LLC
To: BANK OF AMERICA, N.A.
Reel/Frame 023373/0684 →