IP Library › Granted Patent US 8,685,429
Granted Patent B2
US 8,685,429 · App. 11/642,171 · Granted Apr 1, 2014

Shaped bodies and methods for their production and use

View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 8,685,429
App. No.
11/642,171
Granted
Apr 1, 2014
Kind
B2
Abstract

Shaped, composite bodies are provided. One portion of the shaped bodies comprises an RPR-derived porous inorganic material, preferably a calcium phosphate. Another portion of the composite bodies is a different solid material, preferably metal, glass, ceramic or polymeric. The shaped bodies are especially suitable for orthopaedic and other surgical use.

Claims (14)

1. A shaped body comprising: a bioactive filler that comprises 45S5 glass or combeite, and an inorganic material that is the oxidation-reduction reaction product of a metal cation and an oxidizing agent together with a precursor anion oxidizable by said oxidizing agent and that has macro-, meso-, and microporosity and a pore volume of from about 50% to about 95% wherein all or part of said shaped body is permeated with a polymer, wherein said inorganic material comprises calcium phosphate and said polymer comprises gelatin.

2. The shaped body of claim 1 , wherein said body is osteoinductive.

3. The shaped body of claim 1 , wherein said body is osteoconductive.

4. The shaped body of claim 1 , further comprising a medicament.

5. The shaped body of claim 4 , wherein the medicament is growth hormone, antibiotic material, proteins, cell signaling material, steroids, analgesics, or fertility drugs, or combinations thereof.

6. A method of restoring bony defects comprising:

accessing said bony defect;

placing at said bony defect the shaped body of claim 1 ; and

wherein all or part of said shaped body is permeated with a polymer.

7. The method of claim 6 , where said shaped body delivers medicaments internal to the body.

8. The shaped body of claim 1 , wherein said calcium phosphate comprises β-tricalcium phosphate.

9. The method of claim 6 , wherein the shaped body further comprises a medicament.

10. The method of claim 9 , wherein the medicament is growth hormone, antibiotic material, proteins, cell signaling material, steroids, analgesics, or fertility drugs, or combinations thereof.

11. The method of claim 6 , wherein said calcium phosphate comprises β-tricalcium phosphate.

Assignments (4)
RELEASE OF LIEN IN INTELLECTUAL PROPERTY Recorded Jul 26, 2011
From: LB I GROUP INC.
To: ORTHOVITA, INC. (FOR ITSELF AND AS SUCCESSOR BY MERGER TO VITA LICENSING, INC. AND PARTISYN CORP.); ORTHOVITA INTERNATIONAL SERVICES, INC.; VITA SPECIAL PURPOSE CORP.
Reel/Frame 026648/0422 →
MERGER Recorded Dec 1, 2008
From: VITA LICENSING, INC.
To: ORTHOVITA, INC.
Reel/Frame 021901/0354 →
MERGER Recorded Nov 20, 2008
From: VITA SPECIAL PURPOSE CORP
To: VITA LICENSING, INC.
Reel/Frame 021890/0490 →
SECURITY AGREEMENT Recorded Aug 3, 2007
From: VITA SPECIAL PURPOSE CORP.
To: LB I GROUP INC.
Reel/Frame 019649/0291 →