IP Library Granted Patent US 7,727,178
Granted Patent B2
US 7,727,178 · App. 11/643,471 · Granted Jun 1, 2010

Catheter with multiple ultrasound radiating members

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Quick Facts
Patent No.
US 7,727,178
App. No.
11/643,471
Granted
Jun 1, 2010
Kind
B2
Abstract

A catheter for delivering ultrasonic energy and therapeutic compounds to a treatment site within a patient's vasculature comprises a tubular body. The tubular body has a proximal region and a distal region opposite the proximal region. The catheter further comprises a plurality of fluid delivery lumens formed into the tubular body. The catheter further comprises an inner core configured for insertion into the tubular body. The inner core comprises an elongate electrical conductor having a plurality of flattened regions, each flattened region having a first flat side and a second flat side opposite the first flat side. The inner core further comprises a plurality of ultrasound radiating members mounted in pairs to the flattened regions of the elongate electrical conductor. A first ultrasound radiating member is mounted to the first flat side of the elongate electrical conductor, and a second ultrasound radiating member is mounted to the second flat side of the elongate electrical conductor. The catheter further comprises control electronics configured to apply a driving signal to at least two, but fewer than all, of the ultrasound radiating members.

Claims (33)

1. A catheter system for delivering ultrasonic energy and a therapeutic compound to a treatment site within a body lumen, the catheter comprising:

a tubular body having a proximal end, a distal end and an energy delivery section positioned between the proximal end and the distal end;

a fluid delivery lumen extending at least partially through the tubular body and having at least one outlet in the energy delivery section; and

an inner core configured for insertion into the tubular body, the inner core comprising:

an elongate electrical conductor having a plurality of flattened regions, each flattened region having a first flat side and a second flat side opposite the first flat side, and

a plurality of ultrasound radiating members mounted in pairs to the flattened regions of the elongate electrical conductor, such that a first ultrasound radiating member is mounted to the first flat side of the elongate electrical conductor, and a second ultrasound radiating member is mounted to the second flat side of the elongate electrical conductor; and

wiring such that a voltage can be applied from the elongate electrical conductor across the first and second ultrasound radiating members such that the first and second ultrasound radiating members can be driven simultaneously.

2. The catheter system of claim 1 , wherein the fluid delivery lumen comprises a plurality of lumens formed within the tubular body.

3. The catheter system of claim 2 , wherein the fluid delivery lumen comprises three lumens.

4. The catheter system of claim 3 , wherein the three fluid delivery lumens are equally spaced approximately 120 degrees apart from each other around a central axis of the tubular body.

5. The catheter system of claim 1 , further comprising a cooling fluid lumen defined at least in part by an inner surface of the tubular body and an outer surface of the inner core.

6. The catheter system of claim 1 , wherein the catheter system further comprises a plurality of cooling fluid lumens, each cooling fluid lumen being defined at least in part by an inner surface of the tubular body and an outer surface of the inner core.

7. The catheter system of claim 6 , wherein the catheter system includes three cooling fluid lumens that are equally spaced approximately 120 degrees apart from each other about a central axis of the tubular body.

8. The catheter system of claim 1 , wherein the plurality of ultrasound radiating members are electrically coupled into a plurality of electrical groups, each group of ultrasound radiating members independently drivable by a control system.

9. The catheter system of claim 8 , wherein each member of an electrical group is spatially grouped together.

10. The catheter system of claim 8 , wherein each member of an electrical group is positioned adjacent to at least one other member of the electrical group.

11. The catheter of claim 8 , wherein the ultrasound radiating members are allocated into five electrical groups.

12. The catheter of claim 11 , wherein each electrical group comprises twelve ultrasound radiating members.

13. The catheter of claim 1 , wherein the ultrasonic radiating members are ultrasonic transducers in the shape of a rectangular bar.

14. An ultrasonic catheter comprising:

a tubular body having a proximal end, a distal end and a treatment zone located between the distal end and the proximal end;

a plurality of fluid delivery lumens defined within the tubular body;

an inner core comprising at least one ultrasound radiating element; and

a plurality of cooling fluid channels defined between at least an inner surface of the tubular body and an outer surface of the inner core, each cooling fluid channel being positioned generally radially between two fluid delivery lumens.

15. The ultrasonic catheter of claim 14 , wherein the catheter includes three fluid delivery lumens.

16. The ultrasonic catheter of claim 15 , wherein the catheter includes three cooling fluid channels.

17. The ultrasonic catheter of claim 15 , wherein the three fluid delivery lumens spaced approximately 120 degrees radially apart from each other.

18. The ultrasonic catheter of claim 14 , wherein the inner core further comprises an elongate electrical conductor having at least one flattened region, wherein the ultrasound radiating element is mounted to the flattened region.

19. The ultrasonic catheter of claim 14 , wherein the inner core further comprises a plurality of elongate electrical conductors configured to apply a voltage across the ultrasound radiating element.

20. The ultrasonic catheter of claim 14 , further comprising a plurality of ultrasound radiating elements, wherein the plurality of ultrasound radiating elements are electrically coupled into a plurality of electrical groups, each group of ultrasound radiating elements independently drivable by a control system.

21. The ultrasonic catheter of claim 14 , wherein the ultrasonic radiating element is an ultrasonic transducer in the shape of a rectangular bar.

22. The ultrasonic catheter of claim 14 , wherein the treatment zone has a greater acoustic transparency than a region of the tubular body proximal to the treatment zone.

23. The ultrasonic catheter of claim 14 , wherein the inner core can be removably inserted into the tubular body so as to position the ultrasonic radiating element in the treatment zone.

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 9, 2024
From: EKOS LLC
To: BOSTON SCIENTIFIC SCIMED, INC.
Reel/Frame 067042/0823 →
CHANGE OF NAME Recorded Apr 9, 2024
From: EKOS CORPORATION
To: EKOS LLC
Reel/Frame 067043/0077 →
RELEASE OF SECURITY INTEREST Recorded May 15, 2013
From: HERCULES TECHNOLOGY II, L.P.
To: EKOS CORPORATION
Reel/Frame 030421/0867 →
CONFIRMATORY LICENSE Recorded Jun 20, 2011
From: EKOS CORPORATION
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 026465/0057 →
SECURITY AGREEMENT Recorded Jul 16, 2007
From: EKOS CORPORATION
To: HERCULES TECHNOLOGY II, L.P.
Reel/Frame 019550/0881 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 21, 2006
From: WILCOX, ROBERT L.; GENSTLER, CURTIS; ABRAHAMSON, TIM; BARRERE, WM. GERRIT; COHEN, AMY; KEILMAN, GEORGE; OLIVER, LEONARD R.; PESKIN, NATALYA; WILSON, RICHARD R.
To: EKOS CORPORATION
Reel/Frame 018738/0855 →