IP Library Granted Patent US 8,182,443
Granted Patent B1
US 8,182,443 · App. 11/654,904 · Granted May 22, 2012

Drug administration controller

Assignee: MASIMO Corporation
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Quick Facts
Patent No.
US 8,182,443
App. No.
11/654,904
Filed
Jan 17, 2007
Granted
May 22, 2012
Kind
B1
Art Unit
3767
USPC
604/131
Abstract

A drug administration controller has a sensor that generates a sensor signal to a physiological measurement device, which measures a physiological parameter in response. A control output responsive to the physiological parameter or a metric derived from the physiological parameter causes a drug administration device to affect the treatment of a person, such as by initiating, pausing, halting or adjusting the dosage of drugs administered to the person.

Claims (24)

1. A drug administration method comprising:

measuring at least one physiological parameter with a noninvasive optical sensor attached to a patient;

deriving at least one parameter trend for each measured physiological parameter, the trend indicating if the at least one parameter for each measured physiological parameter is increasing or decreasing at a certain rate over a certain time; and

controlling a drug administration device based at least on one of the at least one parameter trends,

wherein the at least one physiological parameter includes perfusion index.

2. The drug administration method according to claim 1 further comprising deriving at least one parameter limit, parameter pattern and a parameter variability.

3. The drug administration method according to claim 1 wherein controlling comprises enabling the drug administration device when perfusion index is trending downward as a marker of pain stimulus.

4. The drug administration method according to claim 1 wherein controlling further comprises pausing the drug administration device when perfusion index is not trending downward.

5. The drug administration method according to claim 1 wherein the at least one physiological parameter includes HbMet and wherein controlling comprises pausing the drug administration device when HbMet is trending upward.

6. The drug administration method according to claim 1 further comprising deriving a parameter limit and wherein the at least one physiological parameter includes HbMet and controlling comprises pausing the drug administration device when HbMet is above HbMet limit.

7. The drug administration method according to claim 1 comprising measuring respiration rate with a noninvasive sensor attached to a patient and deriving a respiration rate trend, wherein controlling comprises pausing the drug administration device when said RR trend is trending downward.

8. The drug administration method according to claim 1 comprising measuring RR with a noninvasive sensor attached to a patient wherein controlling comprises pausing the drug administration device when respiration rate is less than a respiration rate limit.

9. The drug administration method according to claim 1 wherein the at least one physiological parameter includes HbCO.

10. The drug administration method according to claim 1 comprising measuring oxygen saturation with a noninvasive sensor attached to a patient wherein controlling comprises pausing the drug administration device when a number of cyclical desaturations over a given timeframe is greater than a predetermined threshold.

11. A drug administration controller comprising:

at least one noninvasive optical sensor that generates at least one sensor signal in response to a physiological state of a living being;

at least one physiological measurement device that generates measurements of at least one physiological parameter in response to the at least one sensor signal, said at least one physiological parameter including perfusion index;

a rules-based processor that generates a control output in response to at least trends of the physiological parameter measurements, the trends indicating if the physiological parameter measurements are increasing or decreasing at a certain rate over a certain time; and

a drug administration device responsive to one or more control outputs so as to affect the treatment of the living being including at least one of initiating, pausing, halting or adjusting the dosage of administered drugs.

12. The drug administration controller according to claim 11 wherein the drug administration device is one of a drug infusion device and a medical gas inhalation device.

13. The drug administration controller according to claim 12 wherein the at least one sensor comprises:

the optical; and

a sound sensor attached proximate to a neck site so as to measure respiration rate.

14. The drug administration controller according to claim 11 wherein the at least one blood parameter comprises at least one of HbMet and HbCO.

Assignments (4)
RELEASE OF SECURITY INTEREST Recorded Nov 7, 2018
From: JPMORGAN CHASE BANK, NATIONAL ASSOCIATION
To: MASIMO CORPORATION; MASIMO AMERICAS, INC.
Reel/Frame 047443/0109 →
CORRECTIVE ASSIGNMENT TO CORRECT THE NATURE OF CONVEYANCE PREVIOUSLY RECORDED AT REEL: 032784 FRAME: 0864. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY AGREEMENT. Recorded May 27, 2014
From: MASIMO AMERICAS, INC.; MASIMO CORPORATION
To: JPMORGAN CHASE BANK, NATIONAL ASSOCIATION
Reel/Frame 033032/0426 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 29, 2014
From: MASIMO CORPORATION; MASIMO AMERICAS, INC.
To: JPMORGAN CHASE BANK, NATIONAL ASSOCIATION
Reel/Frame 032784/0864 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 11, 2007
From: KIANI, MASSI E.
To: MASIMO CORPORATION
Reel/Frame 019156/0929 →
Continuity (2)
Provisional Application 60759673 · Jan 17, 2006
Provisional Application 60764946 · Feb 2, 2006