IP Library Granted Patent US 9,205,044
Granted Patent B2
US 9,205,044 · App. 11/662,887 · Granted Dec 8, 2015

Aqueous pharmaceutical preparation comprising roflumilast

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Quick Facts
Patent No.
US 9,205,044
App. No.
11/662,887
Granted
Dec 8, 2015
Kind
B2
Abstract

An aqueous pharmaceutical preparation for administration of a slightly soluble PDE4 inhibitor is described.

Claims (2)

1. An aqueous pharmaceutical preparation, which is a clear solution, comprising an active ingredient in a therapeutically effective and pharmacologically acceptable amount and alkoxylated fat, where the active ingredient is selected from the group consisting of roflumilast, salts of roflumilast, the N-oxide of the pyridine residue of roflumilast or salts thereof and poloxamer 188.

2. A process for producing a pharmaceutical preparation according to claim 1 , comprising the steps of (a) dissolving the active ingredient in the alkoxylated fat and adding one or more substances selected from the group consisting of poloxamer 188, polyethylene glycol and propylene glycol preparations; and (b) adding water.

Assignments (7)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 11, 2017
From: TAKEDA GMBH
To: ASTRAZENECA AB
Reel/Frame 041328/0362 →
CHANGE OF NAME Recorded Jul 29, 2015
From: NYCOMED GERMANY HOLDING GMBH
To: TAKEDA GMBH
Reel/Frame 036205/0179 →
MERGER Recorded Jul 28, 2015
From: NYCOMED ASSET MANAGEMENT GMBH
To: NYCOMED GERMANY HOLDING GMBH
Reel/Frame 036201/0478 →
MERGER Recorded Jul 28, 2015
From: TAKEDA GMBH
To: NYCOMED ASSET MANAGEMENT GMBH
Reel/Frame 036193/0224 →
CHANGE OF NAME Recorded Mar 21, 2013
From: NYCOMED GMBH
To: TAKEDA GMBH
Reel/Frame 030062/0599 →
CHANGE OF NAME Recorded Sep 4, 2007
From: ALTANA PHARMA AG
To: NYCOMED GMBH
Reel/Frame 019783/0625 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 12, 2007
From: LINDER, RUDOLF
To: ALTANA PHARMA AG
Reel/Frame 019162/0370 →