IP Library Granted Patent US 8,025,064
Granted Patent B2
US 8,025,064 · App. 11/676,222 · Granted Sep 27, 2011

Methods for attenuating pressure waves in a patient's eye

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Quick Facts
Patent No.
US 8,025,064
App. No.
11/676,222
Granted
Sep 27, 2011
Kind
B2
Abstract

Disclosed herein are methods of treating a patient, comprising providing a compressible attenuation device that is moveable from a first, introduction configuration to a second, implanted configuration. The attenuation device is introduced into a treatment site. In one embodiment, the treatment site is a patient's eye. The volume of the attenuation devices changes in response to pressure changes in the treatment site and attenuates pressure changes in the eye.

Claims (50)

1. A method of treating a patient, comprising the steps of:

providing a compressible attenuation device which is moveable from a first, introduction configuration to a second, implanted configuration;

introducing the attenuation device into the eye while in the first configuration;

transforming the attenuation device within the eye to the second configuration; and

attenuating a pressure change within the eye by reversibly changing the volume of the attenuation device in response to the pressure change.

2. A method as in claim 1 , wherein the transforming step comprises at least partially inflating the attenuation device.

3. A method as in claim 1 , wherein the transforming step comprises permitting the attenuation device to transform under its own bias.

4. A method as in claim 1 , wherein the transforming step minimizes pressure points in the eye.

5. A method as in claim 1 , wherein the attenuating step comprises reducing the volume of the attenuation device by at least about 5%.

6. A method as in claim 1 , wherein the attenuating step comprises reducing the volume of the attenuation device by at least about 10%.

7. A method as in claim 1 , wherein the attenuating step comprises reducing the volume of the attenuation device by at least about 25%.

8. A method as in claim 1 , wherein the attenuation of pressure changes within the eye provides therapeutic benefits after the attenuation device is removed.

9. A method as in claim 1 , wherein the compressible attenuation device is conformable to the shape of the eye.

10. A method as in claim 1 , wherein the configuration of the attenuation device minimizes pressure points in the eye.

11. A method of attenuating or deflecting pressure in a patient's eye structure, comprising placing an attenuator in communication with the eye, exposing the attenuator to an increase in pressure within the eye, and attenuating the increased pressure.

12. A method of attenuating pressure in a patient's eye as in claim 11 , wherein the placing step comprises placing the attenuator intraocularly.

13. A method of attenuating pressure in a patient's eye structure as in claim 11 , wherein the attenuation is accomplished by a reduction in volume of the attenuator.

14. A method of attenuating pressure in a patient's eye structure as in claim 13 , wherein the reduction in volume is responsive to the increase in pressure.

15. A method as in claim 13 , wherein the attenuating step comprises reducing the volume of the attenuator by at least about 5%.

16. A method as in claim 13 , wherein the attenuating step comprises reducing the volume of the attenuator by at least about 10%.

17. A method as in claim 13 , wherein the attenuating step comprises reducing the volume of the attenuator by at least about 25%.

18. A method of attenuating pressure in a patient's eye structure as in claim 12 , wherein the attenuator comprises a compressible wall.

19. A method of treating glaucoma, comprising the steps of identifying a patient at risk for glaucoma; and positioning a compressible pressure attenuator in an eye of the patient.

20. A method of treating glaucoma as in claim 19 , wherein the positioning step comprises carrying the attenuator intraocularly on a deployment device.

21. A method of treating glaucoma as in claim 19 , further comprising the step of removing the attenuator.

22. A method of treating a patient, comprising:

providing a compressible attenuator which is moveable from a first, introduction configuration to a second, implanted configuration;

introducing the attenuator into an eye of the patient while in the first configuration;

transforming the attenuator within the body to the second configuration; and attenuating a pressure spike within the eye by reversibly reducing the volume of the attenuator in response to the pressure spike.

23. A method as in claim 22 , wherein the introducing step comprises introducing the attenuator intraocularly.

24. A method as in claim 22 , wherein the transforming step comprises at least partially inflating the attenuator.

25. A method as in claim 22 , wherein the transforming step comprises permitting the attenuator to transform under its own bias.

26. A method as in claim 22 , wherein the attenuating step comprises reducing the volume of the attenuator by at least about 5%.

27. A method as in claim 22 , wherein the attenuating step comprises reducing the volume of the attenuator by at least about 10%.

28. A method as in claim 22 , wherein the attenuating step comprises reducing the volume of the attenuator by at least about 25%.

29. A method as in claim 22 , further comprising the step of removing the attenuator from the eye.

30. A method as in claim 29 , wherein removing the attenuator comprises deflating the attenuator.

31. A method as in claim 29 , wherein removing the attenuator comprises at least partially dissolving the attenuator.

32. A method as in claim 22 , wherein the compressible attenuator comprises a wire frame.

33. A method of treating a patient, comprising the steps of:

providing a compressible attenuation device that is moveable from a first, introduction configuration to a second, implanted configuration;

introducing the attenuation device into a treatment site while in the first configuration; and

transforming the attenuation device within the treatment site to the second configuration.

34. A method as in claim 33 , wherein the treatment site comprises the eye.

35. A method as in claim 33 , wherein the transforming step comprises at least partially inflating the attenuation device.

36. A method as in claim 33 , wherein the transforming step comprises permitting the attenuation device to transform under its own bias.

37. The method of claim 33 , further comprising attenuating a pressure change within the treatment site by reversibly changing the volume of the attenuation device in response to the pressure change.

38. A method as in claim 37 , wherein the attenuating step comprises reducing the volume of the attenuation device by at least about 5%.

39. A method as in claim 37 , wherein the attenuating step comprises reducing the volume of the attenuation device by at least about 10%.

40. A method as in claim 37 , wherein the attenuating step comprises reducing the volume of the attenuation device by at least about 25%.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 24, 2019
From: ATTENUEX TECHNOLOGIES, INC.
To: SOLACE THERAPEUTICS, INC.
Reel/Frame 049282/0097 →
LICENSE Recorded Jul 10, 2008
From: ATTENUEX TECHNOLOGIES, INC.
To: CASCADE OPHTHALMICS, INC.
Reel/Frame 021222/0643 →
LETTER AGREEMENT Recorded Jul 10, 2008
From: ATTENUEX TECHNOLOGIES, INC.
To: CASCADE OPHTHALMICS, INC.
Reel/Frame 021222/0731 →
Continuity (7)
Continuation 11314601 · Dec 20, 2005
Continuation 10618571 · Jul 11, 2003
Continuation 10391446 · Mar 17, 2003
Continuation In Part 09723309 · Nov 27, 2000
Provisional Application 60415949 · Oct 3, 2002
Provisional Application 60197096 · Apr 14, 2000
Related Publication 20080027478A1 · Jan 31, 2008