Creatine-fatty acids
View Patent ↗The present invention describes compounds produced from a creatine molecule and a fatty acid molecule. The compounds being in the form of creatine-fatty compounds bound by an amide linkage, or mixtures thereof produced by reacting creatine or derivatives thereof with an appropriate fatty acid in the presence of dichloromethane and a pyridine catalyst, previously reacted with a thionyl halide. The administration of such molecules provides supplemental creatine with enhanced bioavailability and the additional benefits conferred by the specific fatty acid.
1. A compound having the general structure:
wherein R is selected from the group consisting of alkanes and alkenes;
said alkanes and alkenes having from 3 to 21 carbons.
2. The compound according to claim 1 wherein R is an alkane having 3 to 5 carbons.
3. The compound according to claim 1 wherein R is an alkane having 7 to 9 carbons.
4. The compound according to claim 1 wherein R is an alkane having 11 to 13 carbons.
5. The compound according to claim 1 wherein R is an alkane having 15 to 17 carbons.
6. The compound according to claim 1 wherein R is an alkane having 19 to 21 carbons.
7. The compound according to claim 1 wherein R is an alkene having at least one carbon-carbon double bond, comprising 3 to 5 carbons.
8. The compound according to claim 1 wherein R is an alkene having at least one carbon-carbon double bond, comprising 7 to 9 carbons.
9. The compound according to claim 1 wherein R is an alkene having at least one carbon-carbon double bond, comprising 11 to 13 carbons.
10. The compound according to claim 1 wherein R is an alkene having at least one carbon-carbon double bond, comprising 15 to 17 carbons.
11. The compound according to claim 1 wherein R is an alkene having at least one carbon-carbon double bond, comprising 17 to 21 carbons.