Peelable child resistant pharmaceutical blister lidstock
View Patent ↗A peelable lidstock for use with a child resistant pharmaceutical blister is disclosed. The lidstock includes a first layer of white polyester, a second layer of adhesive, a third layer of foil, and a fourth layer of heat seal. The lidstock is strong and provides excellent child resistance and a broad sealing window which facilitates manufacture.
1. A flexible lidstock material providing a lid to cover a blister sheet having one or more recesses each containing a pharmaceutical product, said flexible lidstock comprising:
a) a first layer comprising a push-through resistant, flexible film of white polyester, wherein the white polyester comprises white pigment, having a top surface and an opposite bottom surface, said top surface providing a viewable printable surface for labeling said container;
b) a second layer comprising an adhesive;
c) a third layer comprising a flexible foil having a top surface and an opposite bottom surface, said second layer applied between and adhesively securing said first layer bottom surface to said third layer top surface; and
d) a fourth layer comprising a heat seal disposed on said bottom surface of said third layer to allow said flexible lidstock material to be secured to the blister sheet, wherein the heat seal includes vinyl acrylic heat seal coating.
2. The lidstock material of claim 1 wherein the first layer has a thickness of about 0.002 inches.
3. The lidstock material of claim 1 wherein said first layer top surface includes a print primer.
4. The lidstock material of claim 1 wherein said second layer adhesive is a peelable release adhesive to allow said first layer to be peeled away from said third layer of the lidstock material, said third layer foil being breakable by manually pushing said pharmaceutical product therethrough.
5. The lidstock material of claim 4 wherein the peelable release adhesive has a weight of about 0.6 to 1.4 lbs per Ream.
6. The lidstock material of claim 1 wherein said second layer adhesive is a non-peelable release adhesive and said fourth layer heat seal is a peelable heat seal coating to allow the first, second, and third layers to be peeled away all at once as a single unit from said blister sheet.
7. The lidstock material of claim 1 wherein said second layer adhesive is a non-peelable release adhesive and said fourth layer heat seal is a non-peelable heat seal coating whereby a tool is required to access the pharmaceutical product located in a respective recess.
8. The lidstock material of claim 1 wherein the foil includes a 1200 series aluminum alloy.
9. The lidstock material of claim 8 wherein the aluminum foil alloy is O or H temper.
10. The lidstock material of claim 1 wherein the lidstock material has a Mullen burst strength of about 135-145 pounds per square inch.
11. The lidstock material of claim 1 wherein the lidstock material has a puncture strength of about 45-55 pounds.
12. A child resistant pharmaceutical blister package comprising:
a) a base sheet having a plurality of blisters each having a perimeter and formed in the base sheet to contain a pharmaceutical product in a respective blister; and
b) a flexible lidstock material providing a lid disposed on the base sheet to cover the pharmaceutical product in said plurality of blisters, said flexible lidstock material comprising:
i) a heat seal layer disposed at said perimeters of said blisters on the base sheet, wherein the heat seal layer includes vinyl acrylic heat seal coating;
ii) a flexible foil layer disposed on the heat seal layer;
iii) an adhesive layer disposed on the foil layer opposite said heat seal layer; and
iv) a push-through resistant, flexible film layer of white polyester, wherein the white polyester comprises white pigment, disposed on the adhesive layer opposite said foil layer, said film layer of white polyester having a viewable printable surface located opposite said foil layer for labeling said blister pack.
13. The pharmaceutical blister pack of claim 12 wherein the base sheet comprises poly-vinyl chloride.
14. The pharmaceutical blister pack of claim 12 wherein the film layer of white polyester has a thickness of about 0.002 inches.
15. The lidstock material of claim 12 wherein the film layer of white polyester includes a primer applied to said viewable printable surface of the film layer of white polyester.
16. The pharmaceutical blister pack of claim 12 wherein the adhesive layer comprises a peelable release adhesive having a weight of about 0.6 to 1.4 lbs per Ream.
17. The pharmaceutical blister pack of claim 12 wherein the foil layer includes a 1200 series aluminum alloy.
18. The pharmaceutical blister pack of claim 17 wherein the aluminum foil alloy is O or H temper.
19. The pharmaceutical blister pack of claim 12 wherein the lidstock material has a Mullen burst strength of about 135-145 pounds per square inch.
20. The pharmaceutical blister pack of claim 12 wherein the lidstock material has a puncture strength of about 45-55 pounds.
21. The pharmaceutical blister pack of claim 12 wherein said adhesive is a peelable adhesive and access to the pharmaceutical product is achieved by peeling away the film layer of white polyester and manually pushing the pharmaceutical product through the remaining lidstock material.
22. The pharmaceutical blister pack of claim 12 wherein a peel strength of a seal formed between the lidstock material and the base sheet is at least 4.0 lbs/in.width after the lidstock material is sealed to the base sheet for about 0.2 seconds at 40 psi at 350 degrees F.
23. The pharmaceutical blister pack of claim 12 wherein a peel strength of a seal formed between the lidstock material and the base sheet is at least 4.0 lbs/in.width after the lidstock material is sealed to the base sheet for about 0.5 seconds at 40 psi at 300 degrees F.
24. A flexible lidstock material providing a lid for a blister package, said flexible lidstock material consisting essentially of:
a heat seal layer including vinyl acrylic heat seal coating;
a foil layer disposed on the heat seal layer;
an adhesive layer disposed on the foil layer opposite the heat seal layer; and
a film layer of white polyester, wherein the white polyester comprises a white pigment, disposed on the adhesive layer opposite the foil layer,
wherein the adhesive layer comprises a peelable release adhesive allowing the film layer of white polyester to be peeled away from the remaining lidstock material.
25. The lidstock material of claim 24 wherein a peel strength of a seal between the lidstock material and the blister package is at least 4.0 lbs/in. width after the lidstock material is sealed to the blister package for about 0.2 seconds at 40 psi at 350 degrees F.