Use of CCI-779 as an antineoplastic agent

1. A method of treating a refractory neoplasm in a mammal in need thereof, which comprises providing to said mammal a therapeutically effective amount of CCI-779, wherein said mammal has been previously treated with standard chemotherapy and wherein said refractory neoplasm has progressed following treatment with said standard chemotherapy, wherein said refractory neoplasm is renal cancer.

2. A method of reducing the size of a refractory human renal cell tumor in a human patient, which comprises providing to said human patient a therapeutically effective amount of CCI-779, wherein said human patient has been previously treated with standard chemotherapy and wherein said refractory human renal cell tumor has progressed following treatment with said standard chemotherapy.