IP Library Granted Patent US 7,601,369
Granted Patent B2
US 7,601,369 · App. 11/713,907 · Granted Oct 13, 2009

Composition and method to augment and sustain neurotransmitter production

View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 7,601,369
App. No.
11/713,907
Granted
Oct 13, 2009
Kind
B2
Abstract

This invention describes a method and composition to enhance the synthesis and release of the neurotransmitters by the oral administration of neurotransmitter precursors, along with natural plant substances that stimulate uptake of the neurotransmitters precursors, while adding natural plant substances that activate adenylate cyclase in order to avoid attenuation and prevent pharmacologic tolerance. The invention describes compositions for a medical foods that are designed to improve cognitive function, induced sleep, a improve Parasympathetic function, improve autonomic balance, increase nitric oxide production, reduce blood pressure, increase blood flow, and treat virus infections. The compositions include amino acids such as choline, herbs such ginkgo biloba, and other foods such as coca. The invention also describes the use of physiologic tests such as 24 hour ECG monitoring to create the appropriate combinations and assess the useful proportions.

Claims (17)

1. A method for enhancing epinephrine and norepinephrine neurotransmitter activity, comprising orally administering to a subject in need thereof a composition comprising:

at least one first component selected from the group consisting of tryptophan and 5-hydroxytryptophan in the range of from about 1 mg to about 100 mg;

at least one second component selected from the group consisting of glutamine, predigested protein, Ginkgo biloba , ginseng, cinnamon, nutmeg, and St. John's Wort in the range of from about 1 mg to about 200 mg;

at least one third component selected from the group consisting of cocoa, caffeine, and theobromine in the range of from about 1 mg to about 200 mg;

at least one fourth component selected from the group consisting of neuroexcitatory amino acids, glutamate, glutamic acid, and glutamine in the range of from about 1 mg to about 200 mg; and

hawthorn berry as a fifth component in the range of from about 1 mg to about 200 mg,

wherein the proportions of the five or more components are determined by testing said subject using a physiologic test selected from the group consisting of heart rate, 24 hour Electrocardiogram analysis, blood pressure, body temperature, skin temperature, and a neurotransmitter blood test.

2. The method for enhancing epinephrine and norepinephrine neurotransmitter activity of claim 1 wherein said oral administration is provided in a form selected from the group consisting of capsules, suspension caplets, chewable wafers, tablets, or powders.

3. A method for enhancing acetylcholine neurotransmitter activity, comprising orally administering to a subject in need thereof a composition comprising:

at least one first component selected from the group consisting of choline and acetylcarnitine in the range of from about 20 mg to about 100 mg;

at least one second component selected from the group consisting of tryptophan and 5-hydroxytryptophan in the range of from about 20 mg to about 100 mg;

at least one third component selected from the group consisting of Ginkgo biloba , ginseng, cinnamon, nutmeg, and Echinacea in the range of from about 50 mg to about 100 mg;

at least one fourth component selected from the group consisting of cocoa, caffeine, and theobromine in the range of from about 100 mg to about 200 mg;

at least one fifth component selected from the group consisting of neuroexicitatory amino acids, glutamate, glutamic acid, and glutamine in the range of from about 20 mg to about 100 mg; and

at least one sixth component selected from the group consisting of hawthorn berry and caffeine in the range of from about 20 mg to about 40 mg,

wherein the proportions of the six or more components are determined by testing said subject using a physiologic test selected from the group consisting of heart rate, 24 hour Electrocardiogram analysis, blood pressure, body temperature, skin temperature, and a neurotransmitter blood test.

4. The method for enhancing acetylcholine neurotransmitter activity of claim 3 wherein said oral administration is provided in a form selected from the group consisting of capsules, suspension caplets, chewable wafers, tablets, or powders.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 13, 2010
From: SHELL, WILLIAM E; CHARUVASTRA, ELIZABETH H
To: TARGETED MEDICAL PHARMA, INC.
Reel/Frame 025126/0722 →