Angiogenesis initation and growth
View Patent ↗Methods for promoting angiogenesis comprising administering platelet-rich plasma to a site and stimulating the site with an electromagnetic field. Platelets include platelet-rich plasma and compositions can further include stem cells such as adipose stromal cells and cells derived from bone marrow aspirate. Methods also comprise isolating platelets from a patient's blood, forming a composition including the platelets, delivering the composition to a site in need of treatment, and electrically stimulating the site.
1. A method for promoting angiogenesis at a site on a patient, the method comprising:
obtaining blood compatible with the patient;
isolating platelet-rich plasma by density fractionation of said blood;
administering said platelet-rich plasma to the site;
stimulating the site with an electromagnetic field following administration of said platelet-rich plasma to the site; and
promoting angiogenesis at the site upon application of said electromagnetic field and said platelet-rich plasma to the site, wherein the site on the patient is an ulcer.
2. The method for promoting angiogenesis at a site on a patient as set forth in claim 1 , wherein the ulcer is a venous ulcer, pressure ulcer, or diabetic ulcer.