Demolding aids for silicone hydrogels and related methods
View Patent ↗Compositions and methods for improving demolding polar resin molds used in the production of silicone hydrogel materials are described. The present compositions and methods include the use of one or more reactive demolding agents. The reactive demolding agents react with components of a polymerization mixture to produce a polymerized silicone hydrogel device containing a reactant product of the demolding agent and the other components of the polymerization mixture. Polar resin molds used during the polymerization of the polymerization mixture are more easily separated than substantially identical molds used in the polymerization of a substantially identical material without a reactive demolding agent. The present compositions and methods may be used in the manufacture of silicone hydrogel lenses, such as contact lenses. The demolding aids may also be useful as delensing aids.
1. A method of producing a silicone hydrogel device comprising the steps of:
providing a polymerization composition comprising a silicon-containing monomer or macromer, a keto-alcohol diluent component, and a reactive demolding component, in a polar resin mold;
polymerizing the polymerization composition to form a polymerized silicone hydrogel device; and
separating the polar resin mold to reveal the polymerized silicone hydrogel device with a reduced effort relative to separating a substantially identical polar resin mold containing a polymerized product of a substantially identical composition without the demolding component, wherein said keto-alcohol diluent component is present in an amount of from about 5% to about 50% (w/w).
2. The method of claim 1 , wherein said reactive demolding component comprises an agent selected from the group consisting of acrylic acids, methacrylic acids, derivatives thereof, and mixtures thereof.
3. The method of claim 2 , wherein the reactive demolding component comprises an agent selected from the group consisting of monohydroxyacrylates, dihydroxyacrylates, hydroxy methacrylates, hydroxypropylmethacrylates, methacrylates, hydroxyalkylacrylates, acrylamides, methacrylamides, and mixtures thereof.
4. The method of claim 2 , wherein said reactive demolding component is selected from the group consisting of 2-hydroxyethyl methacrylate, hydroxypropyl methacrylate, methacrylic acid, acrylamide, methacrylamide, hydroxyethyl acrylate, and methylmethacrylate.
5. The method of claim 4 , wherein said reactive demolding component is 2-hydroxyethyl methacrylate.
6. The method of claim 4 , wherein said reactive demolding component is 2-hydroxypropyl methacrylate.
7. The method of claim 1 , wherein the reactive demolding component is present in an amount from about 20% and about 30% (w/w) of said polymerization composition.
8. The method of claim 7 , wherein the reactive demolding component is present in an amount from about 20% and about 35% (w/w) of said polymerization composition.
9. The method of claim 1 , wherein the diluent component is present in an amount from about 7% to about 45% (w/w) of the mixture.
10. The method of claim 9 , wherein the diluent component is present in an amount from about 10% to about 40% (w/w) of the mixture.
11. The method of claim 1 , wherein said polymerization composition further comprising a color component.
12. The method of claim 1 , wherein the keto-alcohol diluent component comprises hydroxymethyl pentanone (HMP).
13. The method of claim 1 , wherein the reactive demolding compound comprises 2-hydroxybutyl methacrylate.
14. The method of claim 1 , wherein the method further comprises the steps of:
combining the silicon-containing monomer or macromer and the keto-alcohol diluent component to form a premix composition;
adding the reactive demolding component to the premix composition to form the polymerization composition; and
placing the polymerization composition in the polar resin mold.