Calcium phosphate complex in acid containing chewing gum
View Patent ↗The present invention relates to chewing gum and confectionery compositions for improving the dental health of mammals, particularly humans. In particular, the compositions may include a gum base or carrier, sweetening agents, casein phosphopeptide-calcium phosphate (CPP-ACP) and food-grade acids. The compositions may be employed to remineralize the tooth surfaces of mammals, as well as impart acid resistance thereto.
1. A chewing gum composition comprising:
(a) a gum base;
(b) at least one non-sugar sweetening agent;
(c) casein phosphopeptide-calcium phosphate in an amount of about 0.5% to about 1.5% by weight of the composition; and
(d) at least one food-grade acid comprising citric acid in an amount of from about 0.5 to about 2.5% by weight of the composition;
wherein said composition provides remineralization of enamel in an amount that is at least about 10% greater than the amount provided by a sweetening agent containing chewing gum composition which comprises an equivalent amount of food-grade acid but which is free of casein phosphopeptide-calcium phosphate; and
wherein said composition provides acid resistance to teeth in an amount that is at least about 4% greater than the amount provided by a sweetening agent containing chewing gum composition which comprises an equivalent amount of food-grade acid but which is free of casein phosphopeptide-calcium phosphate.
2. The chewing gum composition of claim 1 , wherein said gum base is present in amounts of about 5% to about 95% by weight of said composition.
3. The chewing gum composition of claim 1 , wherein said at least one sweetening agent is present in amounts of about 0.001% to about 95% by weight of said composition.
4. The chewing gum composition of claim 1 , wherein said casein phosphopeptide-calcium phosphate is present in amounts of about 0.5% to about 0.769% by weight of said composition.
5. The chewing gum composition of claim 1 , wherein said food-grade acid is present in amounts of about 0.5% to about 0.655% by weight of said composition.
6. The chewing gum composition of claim 1 , wherein said non-sugar sweetening agent is selected from the group consisting of sugarless bulk sweeteners, high-intensity sweeteners and combinations thereof.
7. The chewing gum composition of claim 1 , further comprising at least one flavor.
8. The chewing gum composition of claim 1 , wherein said chewing gum composition comprises a chewing gum product selected from the group consisting of slab, pellet, stick, center-fill gum, deposited gum and compressed gum.
9. The chewing gum composition of claim 8 , wherein said chewing gum product comprises a chewing gum region and a coating region and said casein phosphopeptide-calcium phosphate is located in a region selected from the group consisting of said chewing gum region, said coating region and combinations thereof.
10. The chewing gum composition of claim 8 , wherein said chewing gum product comprises a center-fill gum, said center-fill gum comprising a center-fill region and a gum region at least partially surrounding said center-fill region and said casein phosphopeptide-calcium phosphate is located in a region selected from the group consisting of said gum region, said center-fill region and combinations thereof.
11. The chewing gum composition of claim 1 , wherein said casein phosphopeptide-calcium phosphate is encapsulated.
12. The chewing gum composition of claim 1 , wherein said casein phosphopeptide-calcium phosphate comprises a mixture of said casein phosphopeptide-calcium phosphate in an encapsulated form and said casein phosphopeptide-calcium phosphate in an unencapsulated form.
13. The chewing gum composition of claim 1 , wherein said at least one food-grade acid is encapsulated.
14. The chewing gum composition of claim 1 , wherein said at least one food-grade acid comprises a mixture of said at least one food-grade acid in an encapsulated form and said at least one food-grade acid in an unencapsulated form.
15. The chewing gum composition of claim 1 , wherein said casein phosphopeptide-calcium phosphate and said at least one food-grade acid are encapsulated together.
16. The chewing gum composition of claim 1 , wherein said casein phosphopeptide-calcium phosphate and said at least one food-grade acid are encapsulated separately.
17. The chewing gum composition of claim 1 , wherein said composition comprises a chewing gum product comprising about 18 mg of said casein phosphopeptide-calcium phosphate and about 20 mg of said food-grade acid.
18. The chewing gum composition of claim 1 , wherein said composition provides about 13% tooth remineralization upon mastication.
19. The chewing gum composition of claim 1 , wherein said chewing gum composition comprises a chewing gum product displaying a brand or logo that communicates the presence of said casein phosphopeptide-calcium phosphate and said food-grade acid in amounts sufficient to promote remineralization of tooth surfaces.
20. The chewing gum composition of claim 1 , wherein said chewing gum composition comprises a chewing gum product displaying a brand or logo that communicates the presence of said casein phosphopeptide-calcium phosphate and said food-grade acid in amounts sufficient to impart acid resistance to tooth surfaces.
21. A method of imparting acid resistance to the tooth surface of a mammal, comprising the steps of:
(a) applying a chewing gum product into the oral cavity of the mammal, wherein the chewing gum product comprises:
(i) a gum base;
(ii) at least one non-sugar sweetening agent;
(iii) casein phosphopeptide-calcium phosphate in an amount of about 0.5% to about 1.5% by weight of the composition; and
(iv) at least one food-grade acid in an amount of from about 0.5 to about 2.5% by weight of the composition;
wherein said composition provides remineralization of enamel in an amount that is at least about 10% greater than the amount provided by a sweetening agent containing chewing gum composition which comprises an equivalent amount of food-grade acid but which is free of casein phosphopeptide-calcium phosphate; and
wherein said composition provides acid resistance to teeth in an amount that is at least about 4% greater than the amount provided by a sweetening agent containing chewing gum composition which comprises an equivalent amount of food-grade acid but which is free of casein phosphopeptide-calcium phosphate; and
(b) chewing the chewing gum product for a time sufficient to impart acid resistance to the tooth surface of the mammal.
22. The method of claim 21 , wherein said casein phosphopeptide-calcium phosphate is present in amounts of about 0.5% to about 0.769% by weight of said product.