IP Library Granted Patent US 8,092,448
Granted Patent B2
US 8,092,448 · App. 11/741,524 · Granted Jan 10, 2012

Cryosurgical system with low pressure cryogenic fluid supply

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Quick Facts
Patent No.
US 8,092,448
App. No.
11/741,524
Granted
Jan 10, 2012
Kind
B2
Abstract

A liquid cryogen fluid system for providing cryogenic liquid to a cryoprobe in a cryosurgical system for treating fibroadenomas and other lesions in the body. The system includes a cryoprobe to cryoablate a fibroademona with a treatment regimen that takes less time and consumes less cryogen than currently accepted regimens.

Claims (24)

1. A cryosurgical system comprising

a cryoprobe;

a cryogen source comprising a reservoir of cryogenic liquid, said reservoir comprising a volume of cryogenic liquid and volume of gas;

a supply tube connecting the cryoprobe with the reservoir;

a pressurizing means for pumping pressurized gas into the reservoir;

a fluid pathway communicating from the volume of gas to atmosphere, and a valve disposed in said fluid pathway;

a control system operable to control the pressure pump to pump pressurized gas into the reservoir, and operate the control valve to vent the pressurized gas from the reservoir as necessary maintain pressure within the reservoir in a predetermined pressure range;

wherein the pressurizing means comprises:

an accumulator disposed in parallel between a compressor and the cryogen source; and

a stop valve disposed between the accumulator and compressor combination and the reservoir;

wherein the control system is operable, on command from an operator to initiate cryogen flow to the cryoprobe, to control the pressurizing means and stop valve to charge the accumulator without charging the reservoir for an initial period, and thereafter operate the stop valve to pressurize the dewar from the accumulator and also from the pressurizing means to pressurize the dewar.

2. A cryosurgical system of claim 1 wherein the control system is further operable, on command from an operator to initiate cryogen flow to the cryoprobe, to control the pressurizing means and stop valve to charge the accumulator to a first pressure higher than a desired steady state pressure in the reservoir, without charging the reservoir for an initial period, and thereafter operate the stop valve to pressurize the dewar from the accumulator and also from the pressurizing means to pressurize the dewar, wherein said first pressure is high enough to pressurize the reservoir to the desired steady state pressure in the reservoir.

3. A cryosurgical system of claim 1 wherein the control system is further operable, on command from an operator to initiate cryogen flow to the cryoprobe, to control the pressurizing means and stop valve to charge the accumulator to a first pressure higher than a desired steady state pressure in the reservoir, without charging the reservoir for an initial period, and thereafter operate the stop valve to pressurize the dewar from the accumulator and also from the pressurizing means to pressurize the dewar, wherein said first pressure is high enough to pressurize the reservoir to a second pressure higher than the desired steady state pressure in the reservoir, while continuing operation of the pressure pump and operating the control valve as necessary maintain pressure within the reservoir in a predetermined pressure range.

4. A cryosurgical system comprising:

a cryoprobe

a cryogen source comprising a reservoir of cryogenic liquid, said reservoir comprising a volume of cryogenic liquid and volume of pressurized gas;

a supply tube connecting the cryoprobe with the reservoir

a pressure pump for pumping pressurized gas into the reservoir;

a fluid pathway communicating from the volume of pressurized gas to atmosphere, and a valve disposed in said fluid pathway;

a positioning means for moving the reservoir into sealed connection with the supply tube;

a control system operable to control the pressure pump to pump gas into the reservoir, and operate the positioning means and valve, upon a system fault or system shutdown, to operate the positioning means to maintain or re-establish a sealed connection between the reservoir and supply tube, and to open the valve and vent the pressurized gas in the reservoir to atmosphere.

5. A cryosurgical system of claim 4 further comprising:

a second fluid pathway communicating from the volume of pressurized gas to atmosphere, and a second valve disposed in said second fluid pathway, said second fluid pathway being large enough to vent the pressure in the reservoir within a short time from of 1 to 5 seconds;

wherein the control system operable, upon a system fault or system shutdown, to open the second valve.

Assignments (10)
SECURITY INTEREST Recorded Apr 8, 2026
From: BIOTHERANOSTICS, INC.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; CYTYC CORPORATION; SUROS SURGICAL SYSTEMS, INC.; GYNESONICS, INC.; BOLDER SURGICAL, LLC; FAXITRON BIOPTICS, LLC; HEALTH BEACONS, INC.; HOLOGIC, INC.
To: ROYAL BANK OF CANADA, AS COLLATERAL AGENT
Reel/Frame 075462/0440 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 3, 2021
From: SANARUS TECHNOLOGIES, INC.
To: HOLOGIC, INC.
Reel/Frame 055132/0355 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNOR'S SIGNATURE DATE PREVIOUSLY RECORDED ON REEL 038976 FRAME 0055. ASSIGNOR(S) HEREBY CONFIRMS THE MERGER. Recorded Jul 12, 2016
From: SANARUS TECHNOLOGIES, LLC
To: SANARUS TECHNOLOGIES, INC.
Reel/Frame 039312/0353 →
MERGER Recorded Jun 21, 2016
From: SANARUS TECHNOLOGIES, LLC
To: SANARUS TECHNOLOGIES, INC.
Reel/Frame 038976/0055 →
RELEASE OF SECURITY INTEREST Recorded Apr 3, 2013
From: HORIZON TECHNOLOGY FUNDING COMPANY LLC
To: SANARUS TECHNOLOGIES, LLC
Reel/Frame 030144/0939 →
RELEASE OF SECURITY INTEREST Recorded Oct 15, 2009
From: HORIZON TECHNOLOGY FUNDING COMPANY LLC
To: SANARUS MEDICAL INCORPORATED
Reel/Frame 023373/0658 →
SECURITY AGREEMENT Recorded Oct 15, 2009
From: SANARUS TECHNOLOGIES, LLC
To: HORIZON TECHNOLOGY FUNDING COMPANY LLC
Reel/Frame 023373/0908 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 11, 2009
From: SANARUS MEDICAL, INC.
To: SANARUS TECHNOLOGIES, LLC
Reel/Frame 023220/0001 →
SECURITY AGREEMENT Recorded Oct 2, 2008
From: SANARUS MEDICAL INCORPORATED
To: HORIZON TECHNOLOGY FUNDING COMPANY LLC
Reel/Frame 021651/0897 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 30, 2007
From: DELONZOR, RUSSELL L.
To: SANARUS MEDICAL, INC.
Reel/Frame 019671/0677 →