Preparation of amino acid-fatty acid anhydrides
View Patent ↗The present invention describes compounds produced from an amino acid molecule and a fatty acid molecule. The compounds being in the form of amino-fatty acid compounds being bound by an anhydride linkage, or mixtures thereof made by reacting amino acids or derivatives thereof with an appropriate fatty acid previously reacted with a thionyl halide. The administration of such molecules provides supplemental amino acids with enhanced bioavailability and the additional benefits conferred by the specific fatty acid.
1. A compound having the general structure:
wherein R is selected from the group consisting of alkanes and alkenes;
said alkanes and alkenes having from 3 to 21 carbons.
2. The compound according to claim 1 wherein R is an alkane having 3 to 5 carbons.
3. The compound according to claim 1 wherein R is an alkane having 7 to 9 carbons.
4. The compound according to claim 1 wherein R is an alkane having 11 to 13 carbons.
5. The compound according to claim 1 wherein R is an alkane having 15 to 17 carbons.
6. The compound according to claim 1 wherein R is an alkane having 19 to 21 carbons.
7. The compound according to claim 1 wherein R is an alkene having at least one carbon-carbon double bond, comprising 3 to 5 carbons.
8. The compound according to claim 1 wherein R is an alkene having at least one carbon-carbon double bond, comprising 7 to 9 carbons.
9. The compound according to claim 1 wherein R is an alkene having at least one carbon-carbon double bond, comprising 11 to 13 carbons.
10. The compound according to claim 1 wherein R is an alkene having at least one carbon-carbon double bond, comprising 15 to 17 carbons.
11. The compound according to claim 1 wherein R is an alkene having at least one carbon-carbon double bond, comprising 17 to 21 carbons.
12. The compound of claim 11 having a molecular weight of between about 450 and about 495.
13. A compound having the general structure:
wherein R 1 is selected from the group consisting of alkanes and alkenes;
wherein R 2 is selected from the group consisting of hydrogen, methyl, isopropyl, isobutyl, sec butyl, acetylamide, propylamide, and butyl-1-amine;
said alkanes and alkenes having from 3 to 21 carbons.
14. The compound according to claim 13 wherein R 1 is an alkane having 3 to 5 carbons.
15. The compound according to claim 13 wherein R 1 is an alkane having 7 to 9 carbons.
16. The compound according to claim 13 wherein R 1 is an alkane having 11 to 13 carbons.
17. The compound according to claim 13 wherein R 1 is an alkane having 15 to 17 carbons.
18. The compound according to claim 13 wherein R 1 is an alkane having 19 to 21 carbons.
19. The compound according to claim 13 wherein R 1 is an alkene having at least one carbon-carbon double bond, comprising 3 to 5 carbons.
20. The compound according to claim 13 wherein R 1 is an alkene having at least one carbon-carbon double bond, comprising 7 to 9 carbons.
21. The compound according to claim 13 wherein R 1 is an alkene having at least one carbon-carbon double bond, comprising 11 to 13 carbons.
22. The compound according to claim 13 wherein R 1 is an alkene having at least one carbon-carbon double bond, comprising 15 to 17 carbons.
23. The compound according to claim 13 wherein R 1 is an alkene having at least one carbon-carbon double bond, comprising 17 to 21 carbons.