Production of isoprenoids
View Patent ↗The invention provides a biological method of producing isoprenoids.
1. A recombinant yeast comprising one or more heterologous nucleic acid molecules encoding:
a. an enzyme that converts pyruvate and D-glyceraldehyde 3-phosphate to 1-deoxyxylose 5-phosphate; and,
b. an enzyme that converts 1-deoxy-D-xylulose 5-phosphate to 2-C-methyl-D-erythritol 4-phosphate;
wherein, each of the encoded enzymes is a bacterial enzyme.
2. The yeast of claim 1 wherein the one or more heterologous nucleic acid molecules are on one or more plasmids.
3. The yeast of claim 1 wherein the one or more heterologous nucleic acid molecules are integrated into a chromosome.
4. The yeast of claim 1 wherein the one or more heterologous nucleic acid molecules are under inducible control.