IP Library Granted Patent US 7,942,845
Granted Patent B2
US 7,942,845 · App. 11/765,245 · Granted May 17, 2011

Needle-free injector and process for providing serial injections

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Quick Facts
Patent No.
US 7,942,845
App. No.
11/765,245
Granted
May 17, 2011
Kind
B2
Abstract

Needle-free injection devices having a drive assembly to provide an operative force to effect an injection and a dosing assembly to prepare the device for a subsequent injection. In some embodiments, the dosing assembly is configured to transfer injectate from an injectate source to the injectate assembly. In some embodiments, a portion of energy available to the drive assembly urges the injectate towards the injectate assembly. In some embodiments, the device includes a nozzle assembly having one or more ports.

Claims (20)

1. A needle-free injection device for delivering serial injections comprising:

a body configured to house a plurality of systems;

a delivery system adapted to deliver an injection, the delivery system comprising:

an injectate assembly adapted to eject a volume of injectate responsive to application of an operative force to the injectate assembly, the injectate assembly having a nozzle assembly including a chamber and one or more ports, each terminating in an outlet orifice, the nozzle assembly further including a plunger selectively movable within the chamber;

a drive assembly adapted to provide the operative force to move the plunger using energy from an energy supply; and

a dosing assembly configured to transfer injectate from an injectate source to the injectate assembly, wherein a portion of energy available to the drive assembly urges injectate from the injectate source to the injectate assembly; and

an actuation system adapted to actuate the delivery system for delivery of an injection, the actuation system comprising:

a trigger assembly configured to restrict selectively operation of the drive assembly.

2. The device of claim 1 , wherein the energy supply is a compressed gas source, the drive assembly includes a supply valve assembly having one or more valves configured to control gas flow from the energy supply to an energy reserve, and the trigger assembly is adapted to actuate selectively the supply valve assembly.

3. The device of claim 2 , wherein the supply valve assembly includes at least two valves and the trigger assembly is adapted to actuate the valves independently of one another.

4. The device of claim 2 , wherein the supply valve assembly is configured to control gas flow along a sealing path that is configured to seal the energy reserve and a drive path that is configured to fill the energy reserve.

5. The device of claim 4 , wherein a portion of the supply valve assembly is configured to slide and thereby align one or more channels to selectively open the sealing and drive paths.

6. The device of claim 4 , wherein the supply valve assembly includes at least two valves that are independently actuated to control gas flow along the sealing path and the drive path.

7. The device of claim 1 , wherein the injectate source is mounted to the dosing assembly and remains mounted to the dosing assembly during an injection sequence.

8. A delivery system for a needle-free injection device comprising:

an injectate assembly adapted to eject a volume of injectate responsive to application of an operative force to the injectate assembly;

a drive assembly adapted to provide the operative force to the injectate assembly using compressed gas, the drive assembly including a supply valve assembly configured to receive the compressed gas from a gas source and direct the compressed gas along a sealing path configured to seal a storage reservoir and a drive path configured to fill the storage reservoir; and

a dosing assembly configured to fluidly couple an injectate source with the injectate assembly, wherein a portion of the gas received by the supply valve assembly urges injectate from the injectate source into the dosing assembly.

9. The delivery system of claim 8 , wherein excess gas in the sealing path is directed along a feed assist path to urge injectate from the injectate source into the dosing assembly.

10. The delivery system of claim 8 , wherein a portion of the supply valve assembly is configured to slide to selectively open the sealing path and the drive path.

Assignments (4)
MERGER Recorded Feb 2, 2021
From: GENETRONICS, INC.
To: INOVIO PHARMACEUTICALS, INC.
Reel/Frame 055114/0784 →
RELEASE OF SECURITY INTEREST Recorded Mar 28, 2016
From: PARTNERS FOR GROWTH LP
To: BIOJECT MEDICAL TECHNOLOGIES INC. & BIOJECT INC.
Reel/Frame 038265/0229 →
SECURITY AGREEMENT Recorded Sep 4, 2007
From: BIOJECT, INC.
To: PARTNERS FOR GROWTH, L.P.
Reel/Frame 019773/0642 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 19, 2007
From: WILLIAMSON, DANIEL E.; BEYLUND, RYAN R.; DAELLENBACH, KEITH K.
To: BIOJECT INC.
Reel/Frame 019451/0630 →