IP Library Granted Patent US 8,552,013
Granted Patent B2
US 8,552,013 · App. 11/779,828 · Granted Oct 8, 2013

Heterocyclic compounds based on N

Inventors: Igor Popa (Olomouc, CZ); Jan Holub (Olomouc, CZ); René Lenobel (Stemberk, CZ); Stefaan Werbrouck (Harelbeke, BE); Karel Dolezal (Vidce, CZ); Miroslav Strnad (Olomouc, CZ); Marek Zatloukal (Sumperk, CZ); Frank J. Massino (Napa, CA)
Assignee: USTAV Experimentalni Botaniky Akademie Ved Ceske Republiky
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Quick Facts
Patent No.
US 8,552,013
App. No.
11/779,828
Granted
Oct 8, 2013
Kind
B2
Abstract

Novel heterocyclic derivatives based on N 6 -substituted adenine, having anticancer, mitotic, immunosuppressive and antisenescent properties for plant, animal and human cells and methods of their preparation. Included are also pharmaceutical compositions, cosmetic preparations and growth regulators, which contain these derivatives as active compound and the use of these derivatives for the preparation of drugs, cosmetic preparations, in biotechnological processes, in cosmetics and in agriculture.

Claims (3)

1. A cosmetic composition comprising 6-(4-hydroxybenzylamino)purine.

2. A method for inhibiting ageing and senescence of mammalian epidermal cells, said method comprising administering 6-(4-hydroxybenzylamino)purine to a mammal in need of such treatment.

3. A method of claim 2 , wherein the mammalian epidermal cells are fibroblasts.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 28, 2007
From: DOLEZAL, KAREL; POPA, IGOR; HOLUB, JAN; LENOBEL, RENE; WERBROUCK, STEFAAN; STRNAD, MIROSLAV; ZATLOUKAL, MAREK
To: USTAV EXPERIMENTALNI BOTANIKY AKADEMIE VED CESKE REPUBLIKY
Reel/Frame 019945/0876 →
Priority Claims (1)
CZ 2001-2818 · Aug 2, 2001 · national
Continuity (2)
Continuation In Part 10485091
Related Publication 20080014227A1 · Jan 17, 2008