A method of treating or ameliorating an indication of mucosal or adjacent tissue comprising periodically applying to mucosa at or adjacent to disease affected tissue a rinse comprising: an effective amount of appropriate composition of herbal bioactive comprising active(s) of one or more of Sambucus nigra, Centella asiatica or Echinacea purpurea ; an antimicrobially effective amount of a quaternary ammonium surfactant; and optionally a polymer or mixture of polymers effective to coat said tissue and entrap said extract(s).
1. An oral rinse comprising an anti-gingivitis effective amount of herbal extracts of Sambucus nigra, Centella asiatica and Echinacea purpurea defining a weight amount of plant extract solids in the rinse, wherein Sambucus nigra extract is more than 50% to 90% by weight of the plant extract solids and Centella asiatica is 1% to less than 50% by weight of the plant extract solids; a plasticizer in an amount from 10 to 45% by weight of the rinse; and an antimicrobially effective amount of a surfactant that is a 1-alkylpyridinium salt, where alkyl is C8-C36, the surfactant present in an amount from 0.01 to 0.08% of the rinse by weight.
2. The rinse of claim 1 , wherein the 1-alkylpyridinium salt is a cetylpyridinium salt.
3. The rinse of claim 1 , wherein Sambucus nigra extract comprises 60 to 99% by weight of plant extract solids in the rinse.
4. The rinse of claim 3 , wherein Centella asiatica extract comprises from 5 to 40% by weight of plant extract solids in the rinse.
5. A kit for the treatment of an indication of the mucosa or adjacent tissue comprising the oral rinse of claim 1 ; and a film, patch or an adhesive solid formulation comprising a plant extract of Sambucus nigra.
6. The rinse of claim 1 , wherein the rinse is essentially free of added synthetic polymers.
7. The rinse of claim 4 , wherein Echinacea purpurea extract comprises 1 to 20% by weight of plant extract solids in the rinse.
8. The rinse of claim 1 , wherein the plasticizer is propylene glycol.