IP Library › Granted Patent US 7,449,553
Granted Patent B2
US 7,449,553 · App. 11/783,246 · Granted Nov 11, 2008

Antibody that binds ceramidase

View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 7,449,553
App. No.
11/783,246
Granted
Nov 11, 2008
Kind
B2
Abstract

A neutral/alkaline ceramidase derived from a mammal; an antibody specifically binding thereto; a probe and primer which are capable of specifically hybridizing thereto; a method for producing the ceramidase by a genetic engineering means; a method for detecting the ceramidase or the gene; and a method of controlling an amount of a ceramide in a cell and/or in a tissue. The present invention is useful as a reagent for lipid engineering for analyzing a structure, functions, and the like of a ceramide, and in its applications to diseases associated with the ceramide metabolism.

Claims (2)

1. An isolated antibody or a fragment thereof, which specifically binds to an isolated polypeptide comprising the amino acid sequence of SEQ ID NO: 14, wherein said polypeptide possesses ceramidase activity.

2. A kit comprising the antibody or a fragment thereof of claim 1 .