Calibration of analyte measurement device
A calibration system suitable for calibrating non-invasive glucose concentration measurement systems includes one or more continuous glucose measurement devices with the ability to make continuous glucose concentration measurements at multiple regions. The system can accumulate measurement data over period of time and can process the accumulated measurement data to generate calibration related data which is used to adjust the values of one or more parameters in at least one glucose measurement device to achieve and maintain accurate performance of the continuous glucose concentration measurement device.
1 . A method for calibrating a glucose level measurement device comprising:
measuring glucose levels in at least two different regions to form measurement data;
accumulating said measurement data over a period of time to form accumulated data;
processing said accumulated data to generate calibration data; and
using said calibration data to calibrate said glucose level measurement device.
2 . The method of claim 1 , wherein the glucose measurements at different regions are made concurrently.
3 . The method of claim 1 , wherein the glucose measurements at different regions are made continuously.
4 . The method of claim 1 , wherein the different regions are different depths within tissue.
5 . The method of claim 1 , wherein the different regions are tissue at different locations of the body.
6 . The method of claim 1 , wherein the different regions differ by one region being tissue and another region being blood.
7 . The method of claim 1 , wherein the accumulated measurement data is processed by correlating it with previously acquired measurement data.
8 . The method of claim 1 , wherein the accumulated measurement data is processed to determine temporal offset data.
9 . The method of claim 8 , wherein the temporal offset data is correlated with previously generated measurement data to generate calibration data.
10 . The method of claim 1 , wherein the calibration data is used to adjust parameters of a glucose level measurement device.
11 . The method of claim 1 , wherein the glucose level measurement device is a continuous glucose level measurement device.
12 . The method of claim 1 , wherein the glucose level measurement device is a continuous non-invasive glucose level measurement device.
13 . A system for calibrating a glucose level measurement device, said system comprising:
at least one monitor, said monitor containing electronic circuitry, operable to measure glucose levels in at least two different regions to form measurement data;
an electronic memory operable to accumulate said measurement data over a period of time to form accumulated data;
a processor operable to process said accumulated data to generate calibration data; and
said electronic circuitry operable to access said calibration data and operable to adjust parameters depending on said calibration data to modify said monitor in its measurement of glucose levels whereby calibration of said glucose level measurement device is achieved.
14 . An apparatus for calibrating a glucose level measurement device comprising:
means for measuring glucose levels in at least two different regions to form measurement data;
means for accumulating said measurement data over a period of time to form accumulated data;
means for processing said accumulated data to generate calibration data;
means for using said calibration data, wherein said use enables calibration of said glucose level measurement device.
15 . The apparatus of claim 14 , wherein the glucose measurements at different regions are made concurrently.
16 . The apparatus of claim 14 , wherein the glucose measurements at different regions are made continuously.
17 . The apparatus of claim 14 , wherein the different regions are different depths within tissue.
18 . The apparatus of claim 14 , wherein the different regions are tissue at different locations of the body.
19 . The apparatus of claim 14 , wherein the different regions differ by one region being tissue and another region being blood.
20 . The apparatus of claim 14 , wherein the accumulated measurement data is processed by correlating it with previously acquired measurement data.
21 . The apparatus of claim 14 , wherein the accumulated measurement data is processed to determine temporal offset data.
22 . The apparatus of claim 21 , wherein the temporal offset data is correlated with previously generated measurement data to generate calibration data.
23 . The apparatus of claim 14 , wherein the calibration data is used to adjust parameters of the glucose level measurement device.
24 . The apparatus of claim 14 , wherein the glucose level measurement device is a continuous glucose level measurement device.
25 . The apparatus of claim 14 , wherein the glucose level measurement device is a continuous non-invasive glucose level measurement device.