IP Library Granted Patent US 7,442,299
Granted Patent B2
US 7,442,299 · App. 11/799,376 · Granted Oct 28, 2008

Ion exchange porous resins for solid phase extraction and chromatography

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Quick Facts
Patent No.
US 7,442,299
App. No.
11/799,376
Granted
Oct 28, 2008
Kind
B2
Abstract

Embodiments of the present invention are directed to porous resins for solid phase extractions. The resins feature at least one hydrophobic component, at least one hydrophilic component and at least one ion exchange functional group. The resins exhibit superior wetting and ion exchange performance.

Claims (33)

1. A solid phase extraction cartridge comprising a porous resin packed inside an open-ended container, said porous resin comprising at least one ion-exchange functional group, at least on hydrophilic polar component and at least on hydrophobic component, wherein said porous resin is a compound of formula I:

and salts thereof,

wherein the order of A, B and C may be random, block, or a combination of random and block;

wherein

1

100

<

(

p

+

n

)

m

<

100

1

and

1

500

<

p

n

<

100

1

;

wherein A is selected from the group consisting of

wherein B is selected from the group consisting of

wherein C is A or modified A, wherein modified A is selected from the group consisting of

and

wherein X is selected from the group consisting of SO 3 H, CH 2 CO 2 H, CH 2 CH(CO 2 H) 2 , CO 2 H, PO 3 H 2 , PO 2 H 2 , CH 2 PO 3 H 2 , CH 2 CI, CH 2 NH 2 ,

CH 2 N[(CH 2 ) y CH 3 ] 2 wherein y is any integer from 0 to 18, CH 2 N+[(CH 2 ) y′ CH 3 ] 3 D − wherein y′ is any integer from 0 to 18 and D − is an anion, SO 2 NHR wherein R is polyethylenimine, and CH 2 NHR wherein R is polyethylenimine.

2. The solid phase extraction cartridge of claim 1 wherein said porous resin is a sulfonated poly (divinylbenzene-co-N-vinylpyrrolidone).

Assignments (1)
MERGER Recorded Jun 17, 2009
From: WATERS INVESTMENTS LIMITED
To: WATERS TECHNOLOGIES CORPORATION
Reel/Frame 022835/0383 →