IP Library › Granted Patent US 9,220,760
Granted Patent B2
US 9,220,760 · App. 11/799,594 · Granted Dec 29, 2015

Method of modulating the proliferation of medullary thyroid carcinoma cells

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Quick Facts
Patent No.
US 9,220,760
App. No.
11/799,594
Granted
Dec 29, 2015
Kind
B2
Abstract

The present invention is directed to a method of decreasing the rate of proliferation of medullary thyroid carcinoma cells which comprises contacting medullary thyroid carcinoma cells with one or more SSTR2 agonist. A somatostatin receptor antagonist having the formula Cpa-cyclo(D-Cys-4-Pal-D-Trp-Lys-Thr-Cys)-Nal-NH 2 is also disclosed.

Claims (1)

1. A somatostatin type-2 receptor antagonist comprising the formula Cpa-cyclo(D-Cys-4-Pal-D-Trp-Lys-Thr-Cys)-Nal-NH 2 (SEQ ID NO: 6) or a pharmaceutically acceptable salt thereof.

Assignments (7)
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNOR NAME PREVIOUSLY RECORDED ON REEL 296336 FRAME 0777. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jan 5, 2016
From: SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S.
To: IPSEN PHARMA S.A.S.
Reel/Frame 037430/0194 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ADDRESS PREVIOUSLY RECORDED ON REEL 023034 FRAME 0251. ASSIGNOR(S) HEREBY CONFIRMS THE ADDRESS SHOULD BE 65 QUAI GEORGES GORSE, 92100 BOULOGNE-BILLANCOURT, FRANCE. Recorded Jan 16, 2013
From: SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATION SCIENTIFIQUES (S.C.R.A.S.)
To: IPSEN PHARMA S.A.S.
Reel/Frame 029636/0777 →
CHANGE OF NAME Recorded Jul 31, 2009
From: SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATION SCIENTIFIQUES (S.C.R.A.S.)
To: IPSEN PHARMA S.A.S.
Reel/Frame 023034/0251 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 24, 2007
From: UBERTI, ETTORE C. DEGLI; ZATELLI, MARIA C.
To: FERRARA, UNIVERSITY OF
Reel/Frame 019870/0227 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 21, 2007
From: COY, DAVID H.
To: ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE
Reel/Frame 019868/0626 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 15, 2007
From: BIOMEASURE, INCORPORATED
To: SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S.
Reel/Frame 019746/0147 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 14, 2007
From: CULLER, MICHAEL DEWITT
To: BIOMEASURE, INCORPORATED
Reel/Frame 019732/0405 →