IP Library Granted Patent US 8,657,873
Granted Patent B2
US 8,657,873 · App. 11/801,075 · Granted Feb 25, 2014

System for improving cardiac function

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Quick Facts
Patent No.
US 8,657,873
App. No.
11/801,075
Granted
Feb 25, 2014
Kind
B2
Abstract

A system for improving cardiac function is provided. A foldable and expandable frame having at least one anchoring formation is attached to an elongate manipulator and placed in a catheter tube while folded. The tube is inserted into a left ventricle of a heart where the frame is ejected from the tube and expands in the left ventricle. Movements of the elongate manipulator cause the anchor to penetrate the heart muscle and the elongate manipulator to release the frame. The installed frame minimizes the effects of an akinetic portion of the heart forming an aneurysmic bulge.

Claims (28)

1. A device for partitioning a patient's ventricle into a primary productive portion and a secondary non-productive portion, the device comprising:

an expandable frame formed of a plurality of ribs having distal ends secured to a central hub and free outwardly flared proximal ends, wherein in an expanded, deployed configuration the expandable frame is configured to seal off a portion of the patient's ventricle from fluid flow and partition the patient's ventricle to form the primary productive portion;

a plurality of passive tissue penetrating anchors each disposed at the free ends of the ribs to secure the periphery of the partitioning device to the heart chamber.

2. The device of claim 1 wherein the expandable frame has a contracted configuration for delivery to a patient's heart chamber to be partitioned.

3. The device of claim 1 wherein the expandable frame is formed at least in part of a membrane.

4. The device of claim 3 wherein the membrane is formed at least in part of a polymeric fabric.

5. The device of claim 1 wherein the free proximal ends of the ribs are outwardly curved.

6. The device of claim 1 wherein the passive tissue penetrating anchors on the free proximal ends of the ribs are configured to penetrate the tissue lining the heart chamber at an angle of not more than 30° away from a line perpendicular to the center line axis of the partitioning device.

7. The device of claim 1 wherein the pressure receiving surface has radial dimensions from a center line axis of about 10 to about 100 mm.

8. The device of claim 1 wherein the frame has at least 3 ribs.

9. The device of claim 1 wherein the frame is formed at least partially of NiTi, alloy.

10. The device of claim 3 wherein the membrane is formed at least in part of expanded fluoropolymer.

11. The device of claim 3 wherein the expanded fluoropolymer is polytetrafluoroethylene.

12. A partitioning apparatus for partitioning a patient's ventricle to improve cardiac ejection fraction, the apparatus comprising:

a central hub;

an expandable frame having a plurality of ribs with free proximal ends and distal ends secured to the central hub;

a membrane secured to the expandable frame ribs and configured to block fluid flow;

passive tissue penetrating anchors on a plurality of the free proximal ends that are configured to penetrate tissue lining the heart chamber; and

a seal adapted to seal off a volume from fluid flow below an outer edge of the frame from another volume above the outer edge of the frame.

13. The partitioning apparatus of claim 12 wherein the membrane is secured to the proximal side of the ribs.

14. The partitioning apparatus of claim 12 wherein the membrane is secured to the distal side of the ribs.

15. The device of claim 1 wherein the frame has a size and shape adapted to span a portion of the ventricle.

16. The device of claim 3 further comprising a seal adapted to seal off the primary productive portion of the ventricle from the non-productive portion of the ventricle.

17. The device of claim 16 wherein the seal comprises an element extending radially outward from the membrane.

18. The device of claim 17 wherein the seal comprises a plurality of fibers.

19. The partitioning apparatus of claim 12 wherein the seal comprises an element extending radially outward from the membrane.

20. The partitioning apparatus of claim 19 wherein the seal comprises a plurality of fibers.

21. The partitioning apparatus of claim 20 wherein the fibers are configured to interface with the trabeculae.

Assignments (7)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 1, 2017
From: CARDIOKINETIX (ASSIGNMENT FOR THE BENEFIT OF CREDITORS), LLC
To: EDWARDS LIFESCIENCES CORPORATION
Reel/Frame 044348/0922 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 31, 2017
From: CARDIOKINETIX, INC.
To: CARDIOKINETIX (ASSIGNMENT FOR THE BENEFIT OF CREDITORS), LLC
Reel/Frame 044599/0682 →
RELEASE Recorded Mar 11, 2013
From: SILICON VALLEY BANK
To: CARDIOKINETIX, INC.
Reel/Frame 029993/0546 →
RELEASE Recorded Dec 29, 2011
From: SILICON VALLEY BANK
To: CARDIOKINETIX, INC.
Reel/Frame 027504/0897 →
SECURITY AGREEMENT Recorded Jun 15, 2010
From: CARDIOKINETIX, INC.
To: SILICON VALLEY BANK
Reel/Frame 024539/0631 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 20, 2007
From: KHAIRKHAHAN, ALEXANDER; SHARKEY, HUGH R.; NIKOLIC, SERJAN D.
To: SEPTUS INC.
Reel/Frame 019457/0376 →
CHANGE OF NAME Recorded Jun 20, 2007
From: SEPTUS, INC.
To: CARDIOKINETIX INC.
Reel/Frame 019457/0637 →