IP Library › Granted Patent US 40,988
Granted Patent E1
US 40,988 · App. 11/807,588 · Granted Nov 17, 2009

Ligands of the neuropeptide receptor HFGAN72

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Quick Facts
Patent No.
US 40,988
App. No.
11/807,588
Granted
Nov 17, 2009
Kind
E1
Abstract

Polypeptides of HFGAN72 receptor ligands and polynucleotides encoding the polypeptides are provided. Methods of using these polypeptides to diagnose diseases relating to the under- or over-expression of HFGAN72 receptor ligands are also provided. In addition, methods of identifying agonists or antagonists of the interaction of HFGAN72 receptor ligands with the HFGAN72 receptor are provided. Methods of treatment by administering the identified agonists or antagonists to patients in need thereof are further disclosed.

Claims (6)

1. An isolated polypeptide comprising an amino acid sequence selected from the group consisting of: SEQ ID NO:2, SEQ ID NO: 4, SEQ ID NO: 6, SEQ ID NO:8, SEQ ID NO:9, SEQ ID NO:10, and SEQ ID NO:12.

2. An isolated polypeptide comprising the amino acid sequence of SEQ ID NO: 4.

3. An isolated polypeptide comprising the amino acid sequence of SEQ ID NO: 8.

4. An isolated polypeptide comprising the amino acid sequence of SEQ ID NO: 2 .

5. An isolated polypeptide comprising the amino acid sequence of SEQ ID NO: 10 .

6. An isolated polypeptide comprising the amino acid sequence of SEQ ID NO: 12 .

Assignments (1)
CHANGE OF NAME Recorded Jan 6, 2010
From: SMITHKLINE BEECHAM CORPORATION
To: GLAXOSMITHKLINE LLC
Reel/Frame 023731/0740 →