Glycine Reuptake Inhibitors for Treatment of Drug Dependence
The invention relates to a method of treatment or prevention of drug addiction, in particular alcoholism, in humans, comprising administering to a subject, in need thereof, an effective amount of a Gly-T1 inhibitor, in particular N-methyl-N-[[(1R,2S)-1,2,3,4-tetrahydro-6-methoxy-1-phenyl-2-naphthalenyl]methyl glycine or a pharmaceutically acceptable salt thereof.
1 . A method of treatment or prevention of drug addiction in humans, comprising administering to a subject, in need thereof, an effective amount of a Gly-T1 inhibitor.
2 . The method according to claim 1 , wherein the drug addiction is alcoholism.
3 . The method according to claim 1 , wherein the compound is N-methyl-N-[[(1R,2S)-1,2,3,4-tetrahydro-6-methoxy-1-phenyl-2-naphthalenyl]methyl glycine or a pharmaceutically acceptable salt thereof.
4 . The method according to claim 2 , wherein the compound is N-methyl-N-[[(1R,2S)-1,2,3,4-tetrahydro-6-methoxy-1-phenyl-2-naphthalenyl]methyl glycine or a pharmaceutically acceptable salt thereof.