The invention relates to air traps 13 , particularly for chromatography systems, chromatography systems using such air traps and methods of using such chromatography systems, in which the air trap comprises a liquid inlet pipe 33 , a liquid outlet pipe 35 , a substantially cylindrical reservoir 25 between the inlet and outlet pipes 33, 35 , and an air outlet opening, the air outlet opening being openable and closable by means of a valve, wherein the liquid inlet and outlet pipes 33, 35 connect to the reservoir 25 substantially tangentially to the reservoir wall 27 , the inlet pipe 33 at a distance above the outlet pipe 35 , arranged such that during use incoming liquid at a the maximum permitted flow rate travels a spiral path from the inlet pipe 33 to the outlet pipe 35 .
1. An air trap for removing air in a liquid flowing through a chromatography system, wherein the air trap comprises a liquid inlet pipe ( 33 ), a liquid outlet pipe ( 35 ), a substantially cylindrical reservoir ( 25 ) between the inlet and outlet pipes, and an air outlet opening ( 37 ), the air outlet opening being openable and closable by means of a valve ( 38 ), wherein the liquid inlet and outlet pipes ( 33 , 35 ) connect to the reservoir ( 25 ) substantially tangentially to the reservoir wall ( 27 ), the inlet pipe ( 33 ) at a distance above the outlet pipe ( 35 ), arranged such that during use incoming liquid at a flow rate equal to its maximum permitted flow rate travels a spiral path from the inlet pipe ( 33 ) to the outlet pipe ( 35 ), wherein said air trap is a sanitary design.
2. The air trap of claim 1 , wherein a substantially cylindrical protuberance ( 39 ) protrudes axially from the bottom of the reservoir ( 25 ).
3. The air trap of claim 1 , wherein it is designed such that during use incoming liquid at a flow rate equal to its maximum permitted flow rate travels a spiral path from the inlet pipe ( 33 ) to the outlet pipe ( 35 ) and is subject to centrifugal force of at least 1 G.
4. The air trap of claim 1 , wherein it is designed such that during use incoming liquid at a flow rate equal to its maximum permitted flow rate travels a spiral path from the inlet pipe ( 33 ) to the outlet pipe ( 35 ) and is subject to centrifugal force of at least 2 G.
5. A chromatography system comprising a source of liquid, a pump for pumping said liquid from said source via the air trap of claim 1 to a chromatography column.
6. A method for removing air in a liquid flowing through a chromatography system, characterised by the step of operatively providing the system with the air trap of claim 1 .