Isoindoline compounds and methods of making and using the same
The invention encompasses isoindoline compounds, pharmaceutical compositions comprising them, and methods of their use for the treatment, prevention or management of various diseases and disorders. Examples include, but are not limited to, cancer, inflammatory bowel disease and myelodysplastic syndrome.
1. A compound, or a pharmaceutically acceptable salt or solvate thereof, wherein the compound is:
2. A compound, or a pharmaceutically acceptable stereoisomer thereof, wherein the compound is:
3. A pharmaceutical composition comprising a compound of claim 1 or 2 .
4. The pharmaceutical composition of claim 3 , which further comprises a pharmaceutically acceptable carrier or excipient.
5. A dosage form comprising a compound of claim 1 or 2 .
6. The dosage form of claim 5 , which is suitable for oral or parenteral administration.