Chemistry system for clinical analyzer
View Patent ↗A clinical analyzer for determining the presence or amount of an analyte in a sample includes at least one reagent supply and at least one reaction containment device for containing a volume of sample and a volume of said at least one reagent from said at least one reagent supply. A wash-free delivery system introduces reagent into at least one reaction containment device without requiring washing of delivery components.
1. A method for conducting an assay in a clinical analyzer, said method comprising the steps of:
providing a plurality of first disposable metering tips;
providing a plurality of second disposable metering tips;
aspirating a volume of patient sample from a primary patient supply using one of said plurality of second disposable metering tips attached to a metering mechanism of said analyzer;
sealing the dispense end of said second disposable metering tip following aspiration of said volume of patent sample;
storing said sealed second disposable metering tip in an auxiliary patient sample supply as a sample container;
aspirating a volume of reagent from a reagent supply of said clinical analyzer using one of said plurality of first disposable metering tips as attached to a metering mechanism of said clinical analyzer;
dispensing the volume of reagent into a reaction vessel; and
discarding said first disposable metering tip.
2. A method as recited in claim 1 , wherein said reaction vessel is a reaction cuvette.
3. A method as recited in claim 1 , including the step of dispensing a portion of said patient sample from said sealed second disposable metering tip onto a test element prior to said sealing step.
4. A method as recited in claim 3 , wherein said test element is a dry slide element.
5. A method as recited in claim 1 , including the step of optically testing said patient sample in said sealed second disposable metering tip.
6. A method as recited in claim 5 , wherein said optical testing step is performed prior to said storing step.
7. A method as recited in claim 1 , including the step of storing each of said plurality of first disposable metering tips and said plurality of second sealed disposable metering tips in said auxiliary patient sample supply.
8. A method as recited in claim 1 , including the additional steps of:
aspirating a volume of patient sample from the confines of said sealed second disposable metering tip using a metering mechanism of said clinical analyzer, said metering mechanism having attached one of a plurality of third disposable metering tips sized to fit within the confines of said sealed second disposable metering tip; and
dispensing said volume of patient sample from said third disposable tip into said reaction vessel.
9. A method as recited in claim 8 , wherein said patient sample is dispensed into said reaction vessel prior to said volume of reagent.
10. A method as recited in claim 9 , wherein each said first disposable metering tip includes a dispense end, said method including the additional step of placing the dispense end of said first disposable metering tip into direct contact with the volume of patient sample contained within said reaction vessel during said reagent dispensing step.
11. A method of utilizing a combinational clinical analyzer having a dry chemistry system and a wet chemistry system each disposed within a housing, said method comprising the steps of:
providing a plurality of first disposable metering tips;
providing a plurality of second disposable metering tips;
aspirating a volume of patient sample from a primary patient supply of said clinical analyzer using a metering system, said metering system including a metering head having disposed thereon one of said plurality of second disposable metering tips;
sealing the dispense end of said second disposable metering tip and storing said second disposable metering tip in an auxiliary patient sample supply;
aspirating a volume of reagent from a reagent supply using a metering system including a metering head and having disposed thereon one of said plurality of first disposable metering tips;
dispensing said volume of reagent into a reaction vessel; and
discarding said first disposable metering tip.
12. A method as recited in claim 11 , including the additional step of dispensing a portion of said volume of patient sample prior to said sealing step onto a test element.
13. A method as recited in claim 12 , wherein said test element is a slide element used in said dry chemistry system of said combinational analyzer.
14. A method as recited in claim 11 , including the additional steps of:
aspirating a volume of patient sample from the confines of said sealed second disposable metering tip using one of said metering systems, said metering head having attached one of a plurality of third disposable metering tips sized to fit within the confines of said second disposable metering tip; and
dispensing said volume of patient sample from said third disposable tip into said reaction vessel.