Minimally invasive medical device and method for delivery of therapeutic or diagnostic agents into a vessel wall

1. A minimally invasive device for delivering therapeutic or diagnostic agents into a vessel wall, comprising:

an introducer tube;

a tubular member having a proximal end, a distal end, and a first lumen extending therebetween, the tubular member slidably disposed within the introducer tube;

a plurality of hollow delivery struts disposed on the distal end of the tubular member and in fluid communication with the first lumen, each hollow delivery strut adapted to pierce through inner most layers of the vessel wall, and each comprising:

at least one exit port, and

an extension at a distal portion of at least one of the hollow delivery struts, the extension comprising at least one other exit port in fluid communication with the hollow delivery strut,

wherein the extension is a stopper to prevent the delivery strut from piercing through the outer most layers of the vessel wall, the stopper extending from the hollow delivery strut and positioned at a distance of from about 5 mm to about 0.5 mm from a distal tip of the hollow delivery strut.

2. The device of claim 1 , further comprising an endcap affixed to the distal end of the tubular member, the plurality of hollow delivery struts being affixed to a distal face of the endcap.

3. The device of claim 2 , wherein the hollow delivery struts are arranged in a pattern on the distal face of the endcap.

4. The device of claim 1 , wherein the exit port is an opening at a distal tip of the delivery strut.

5. The device of claim 1 , wherein each delivery strut comprises multiple exit ports.

6. The device of claim 5 , wherein the exit ports are arranged around the circumference of the delivery strut.

7. The device of claim 1 , wherein the stopper is disposed about the outer surface of the hollow delivery struts.

8. The device of claim 7 , wherein the stopper is disposed on the outer surface of the delivery struts by welding, adhesive, crimping, or mechanical or chemical fixation.

9. The device of claim 1 , wherein a plurality of exit ports is located on the extension.

10. The device of claim 1 , further comprising at least one other stopper.

11. The device of claim 1 , wherein the delivery struts comprise at least one fixation element.

12. The device of claim 11 , wherein the fixation element is a barb or a hook.

13. The device of claim 1 , further comprising a wire guide positioned in the tubular member.

14. The device of claim 13 , wherein the tubular member further comprises a second lumen for the wire guide.

15. The device of claim 1 , wherein the tubular member comprises a plurality of hollow wires.

16. The device of claim 1 , wherein the tubular member extends from a handle allowing for continued retention of the device after the deployment in the blood vessel and retrieval back into the introducer tube.

17. A method of treating a vessel stenosis comprising

deploying the minimally invasive device of claim 1 into a stenotic vessel wall; and

administering therapeutic or diagnostic agents through the hollow delivery struts into the stenotic vessel wall.

18. The method of claim 17 , further comprising deploying a medical device selected from the group consisting of stent, stent graft, and balloon.

19. A method of treating an aneurysm comprising

deploying the minimally invasive device of claim 1 into an aneurismal vessel wall; and

administering therapeutic or diagnostic agents through the hollow delivery struts into the aneurismal vessel wall.

20. The method of claim 19 , further comprising deploying a medical device selected from the group consisting of stent, stent graft, and balloon.