IP Library Granted Patent US 7,616,801
Granted Patent B2
US 7,616,801 · App. 11/827,909 · Granted Nov 10, 2009

Image handling and display in x-ray mammography and tomosynthesis

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Quick Facts
Patent No.
US 7,616,801
App. No.
11/827,909
Granted
Nov 10, 2009
Kind
B2
Abstract

A method and system for acquiring, processing, storing, and displaying x-ray mammograms Mp tomosynthesis images Tr representative of breast slices, and x-ray tomosynthesis projection images Tp taken at different angles to a breast, where the Tr images are reconstructed from Tp images.

Claims (30)

1. A method of acquiring and displaying x-ray images comprising:

acquiring x-ray mammography image data Mp representative of projection mammography images of patients' breasts and x-ray tomosynthesis image data Tp representative of projection images Tp taken at different angles of an origin of imaging x-rays relative to the patients' breasts, from an acquisition unit configured to selectively acquire said mammography and tomosynthesis image data;

reconstructing at least a subset of the acquired Tp data into reconstructed tomosynthesis image data Tr representative of images of slices of the breasts that have selected orientations and thicknesses; and

displaying concurrently or by toggling at least a selected combination of the Mp and Tr, or Mp and Tp, or Tr and Tp image data using a selected hanging protocol.

2. A method as in claim 1 including generating computer aided detection (CAD) marks indicative of suspected abnormalities in said Mp images and displaying said marks at corresponding locations on Tr images associated with respective Mp images.

3. A method as in claim 1 including generating computer aided detection (CAD) marks indicative of suspected abnormalities in said Tr images and displaying said marks at corresponding locations on Mp images associated with respective Tr images.

4. A method as in claim 1 including generating computer aided detection (CAD) marks indicative of suspected abnormalities in at least some of said images, and displaying Tr images together with CAD marks associated therewith while suppressing concurrent displaying of Tr images that do not have CAD marks associated therewith.

5. A method as in claim 1 including storing Tp image data together with version information indicative of at least one of acquisition configuration used to acquire the Tp image data and reconstruction configuration used for previous reconstruction of Tr images from said Tp image data, thereby enabling later reconstruction of Tr images that match those previously reconstructed form the Tp image data.

6. A method as in claim 1 including storing said Tp image data together with version information related to the acquisition thereof, and further including reconstructing said Tp image data into Tr images using a reconstruction configuration that matches said version information.

7. A method as in claim 1 including storing said Tp image data together with version information and further including providing a reconstruction configuration having at least two different versions of reconstruction software and using a version of the reconstruction software that matches the version information of the Tp image data to reconstruct Tr images therefrom.

8. A method as in claim 1 including reconstruction Tr images from only a subset of the acquired Tp image data, said subset being related to only some of said different angles of at least the x-ray source relative to the breast platform.

9. A method as in claim 1 including reconstructing Tr images representative of at least two breast slices that differ in thickness.

10. A method as in claim 9 including using a maximum intensity projection (MIP) method to reconstruct at least one of said Tr images.

11. A method as in claim 9 using a summing method to reconstruct at least one of said Tr images.

12. A method as in claim 11 in which said summing method comprises a weighted summing method.

13. A method as in claim 9 including toggling between displays of Tr images representative of breast slices having different thicknesses.

14. A method as in claim 1 including computer-processing information contained in at least one of said Tr images to compute a volume of a lesion imaged therein.

15. A system comprising:

an acquisition unit comprising a breast platform, a source of x-rays at one side of the platform and an x-ray imaging device at another side of the platform, said acquisition unit selectively acquiring x-ray mammography image data representative of projection mammography images Mp of patients' breasts on said platform and x-ray tomosynthesis image data representative of tomosynthesis projection images Tp taken at different angles of at least the x-ray source relative to the breast platform;

an image reconstruction unit coupled with the acquisition unit and receiving said image data therefrom and selectively reconstructing at least a subset of the acquired Tp images into reconstructed tomosynthesis images Tr representative of slices of the breasts that have selected orientations and thicknesses; and

a display unit displaying concurrently or by toggling at least a selected combination or subcombinations of the Mp and Tr, or Mp and Tp, or Tr and Tp images for viewing according to a selected hanging protocol.

16. A system as in claim 15 in which said display concurrently displays different Tr images.

17. A system as in claim 16 in which the display toggles between different combinations of said images.

18. A method of displaying x-ray images comprising:

providing x-ray data representative of at least one of (i) tomosynthesis images Tp representative of projection images taken at different angles of an origin of imaging x-rays relative to a patients' breasts, and (ii) reconstructed images Tr reconstructed from selected sets or subsets of said images Tp;

wherein said images Tr are representative of slices of the breasts that have selected orientations and thicknesses; and

selectively displaying stereoscopically selected pairs of at least two of said images Tp or at least two of said images Tr;

including selectively providing images Tr that conform to a first set of imaging planes that are parallel to each other but are at different depth in a patient's breast and a second set of images Tr that also are parallel to each other but are at different depths in the patient's breast, where the two sets of imaging planes are angled to each other, and selectively scrolling through pairs of stereoscopically displayed Tr images, each pair comprising one Tr image from each set.

19. A method of displaying x-ray images as in claim 18 , including:

selectively scrolling through different pairs of images Tp that are stereoscopically displayed, thereby stereoscopically viewing a patient's breast from different angles.

Assignments (7)
RELEASE OF SECURITY INTEREST Recorded Apr 28, 2026
From: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
To: HOLOGIC, INC., ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO DIRECT RADIOGRAPHY CORP.; CYTYC CORPORATION, ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO BIOLUCENT, LLC; CYTYC SURGICAL PRODUCTS, LLC, AS SUCCESSOR-BY-CONVERSION TO CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; GEN-PROBE INCORPORATED, ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE PRODESSE, INC.; SUROS SURGICAL SYSTEMS, INC.
Reel/Frame 075566/0039 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT PATENT NO. 8081301 PREVIOUSLY RECORDED AT REEL: 035820 FRAME: 0239. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY INTEREST RELEASE. Recorded Nov 9, 2017
From: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
To: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
Reel/Frame 044727/0529 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT PATENT NO. 8081301 PREVIOUSLY RECORDED AT REEL: 028810 FRAME: 0745. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY AGREEMENT. Recorded Nov 9, 2017
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
To: GOLDMAN SACHS BANK USA
Reel/Frame 044432/0565 →
SECURITY AGREEMENT Recorded Aug 7, 2015
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; DIRECT RADIOGRAPHY CORP.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 036307/0199 →
SECURITY INTEREST RELEASE REEL/FRAME 028810/0745 Recorded Jun 4, 2015
From: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
To: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
Reel/Frame 035820/0239 →
SECURITY AGREEMENT Recorded Aug 1, 2012
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
To: GOLDMAN SACHS BANK USA
Reel/Frame 028810/0745 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 5, 2007
From: GKANATSIOS, NIKOLAOS A; NIKLASON, LOREN; SHAW, IAN; RUTH, CHRISTOPHER; SMITH ANDREW P; STEIN, JAY A
To: HOLOGIC, INC.
Reel/Frame 019960/0279 →