Devices, systems and methods for retracting, lifting, compressing, supporting or repositioning tissues or anatomical structures
View Patent ↗Devices, systems and methods for retracting, lifting, compressing, supporting or repositioning tissues, organs, anatomical structures, grafts or other structures within the body of human or animal subjects for the purpose of treating a diseases or disorders and/or for cosmetic or reconstructive purposes and/or for research and development purposes or other purposes.
1. A system for retracting, lifting, compressing, supporting or repositioning of an organ or tissue within the body of a human or animal subject, said system comprising:
a first anchor having a connector attached thereto;
a first introducer defining structure independent from the first anchor and useable to deliver and implant the first anchor at a first location within the subject's body, the first introducer configured to cut a pathway through an organ or tissue displaced from and exterior of the first introducer and through which the first anchor is advanced;
a second anchor having a longitudinal axis that is advanceable over the connector; and
a second introducer useable to advance the second anchor over the connector to a second location and to affix the second anchor to the connector wherein the second introducer comprises an elongate shaft having a second anchor delivery lumen and a pusher for advancing the second anchor in a first configuration in which its longitudinal axis is generally parallel to the connector through the second anchor delivery lumen and over the connector to a second configuration in which its longitudinal axis is generally perpendicular to the connector.
2. A system according to claim 1 wherein the connector comprises suture thread.
3. A system according to claim 1 wherein:
the first anchor comprises an elongate tubular member that has a lumen that extends longitudinally therethrough, a distal end opening, a proximal end opening and a slot that extends longitudinally from the proximal end opening to a location between the proximal end opening and the distal end opening.
4. A system according to claim 3 wherein the connector extends through the lumen of the tubular member such that a distal end of the connector extends out of and beyond the distal end opening of the tubular member, the distal end of the connector being non-retractable through the distal end opening.
5. A system according to claim 4 wherein an enlarged region is on the distal end of the connector to deter its retraction in the proximal direction through distal end opening.
6. A system according to claim 4 wherein a knot is tied in the distal end of the connector to deter its retraction in the proximal direction through distal end opening.
7. A system according to claim 3 wherein a cross member extends across the distal end opening and wherein the connector is attached to said cross member to deter the connector from being pulled out of the lumen of the tubular member.
8. A system according to claim 3 wherein the tubular member further comprises one or more protrusions that protrude into the lumen of the tubular member and engage the connector to deter the connector from being pulled out of the lumen of the tubular member.
9. A system according to claim 3 wherein the connector extends coaxially through the lumen of the tubular member and out of its proximal end opening while being delivered into the body and, after the tubular member has been delivered into the subject's body, the connector is pulled through the slot and the tubular member assumes a position where its longitudinal axis is generally perpendicular to an adjacent portion of the connector.
10. A system according to claim 1 wherein the first introducer comprises an elongate shaft that is insertable into the subject's body and a penetrator that is advanceable from the elongate shaft through tissue to said first location, said first anchor with the connector attached thereto deployable from said penetrator after the penetrator has been advanced to the first location.
11. A system according to claim 10 wherein the elongate shaft is configured to be inserted into the subject's urethra and the hollow penetrator is advanceable from the elongate shaft into or through the prostate.
12. A system according to claim 10 wherein the penetrator is sized to be advanced from the urethra and through the prostate to an extracapsular first location and the first anchor is deployable such that it engages an outer aspect of the prostatic capsule.
13. A system according to claim 10 wherein the penetrator is sized to be advanced from the urethra and into the prostate to an intracapsular first location and the first anchor is deployable such that it become implanted within the prostatic capsule.
14. A system according to claim 10 wherein the penetrator is sized to be advanced from the urethra and into the prostate to a subcapsular first location and the first anchor is deployable such that it become implanted at a subcapsular location within the prostate.
15. A system according to claim 10 wherein the first anchor comprises an elongate member that is initially deployed in a first orientation that is substantially parallel to an adjacent portion connector as it is advanced through the penetration tract and subsequently moves to a second orientation that is substantially perpendicular to the connector after it has become implanted at said first location.
16. A system according to claim 15 wherein the first introducer comprises an elongate shaft that is insertable into the subject's body and a hollow penetrator having a penetrator lumen, said hollow penetrator being advanceable from the elongate shaft through tissue to said first location, and wherein said first anchor is initially disposed in the lumen of the hollow penetrator while in said first orientation and subsequently transitionable to said second orientation after being expelled out of the lumen of the hollow penetrator.
17. A system according to claim 10 wherein the penetrator is retractable into the elongate shaft leaving a penetration tract through tissue.
18. A system according to claim 17 wherein the first introducer is removable from the body after the penetrator has been retracted, leaving the first anchor with the connector attached thereto implanted at the first location and the connector extending through said penetration tract.
19. The system according to claim 10 wherein the penetrator includes a needle having a curved longitudinal profile.
20. A system according to claim 1 wherein the first introducer further comprises an endoscope.
21. A system according to claim 20 wherein the endoscope is useable to view advancement of the penetrator.
22. A system according to claim 1 wherein the first introducer further comprises a channel for receiving an endoscope.
23. A system according to claim 22 wherein the channel for receiving an endoscope is configured such that an endoscope may be inserted into said channel and used to view advancement of the penetrator.
24. A system according to claim 22 wherein the elongate shaft is sized to be inserted into the urethra and the channel is sized to receive a cystoscope.
25. A system according to claim 1 wherein the first introducer further comprises a handpiece on the proximal end of the elongate shaft.
26. A system according to claim 25 wherein the handpiece comprises a first actuator for advancing a penetrator and a second actuator for deploying the first anchor from a penetrator.
27. A system according to claim 25 wherein the first introducer further comprises a channel into which an endoscope may be inserted and wherein the handpiece further comprises an endoscope lock that is useable to lock an endoscope at a substantially fixed position within the endoscope channel.
28. A system according to claim 1 wherein the second anchor comprises a member having a hollow passage extending therethrough such that a proximal end of the connector may be inserted into the hollow passage of the second anchor and the second anchor is advanceable over the connector such that the connector slides through the hollow passage until the second anchor has reached the second location.
29. A system according to claim 28 wherein the second anchor further comprises a locking member that is moveable from a non-locked position whereby it allows the connector to slide through the hollow passage to a second position whereby it locks the second anchor at a fixed position on the connector.
30. A system according to claim 29 wherein the locking member comprises a locking pin.
31. A system according to claim 29 wherein the locking member comprises a wedging element that wedges between the connector and an inner wall of the hollow passage.
32. A system according to claim 31 wherein the wedging element comprises an elongate shaft having branches or bristles extending therefrom.
33. A system according to claim 29 wherein the second anchor further comprises a locking member engagement surface that engages the locking member after it has been advanced to its locked position, thereby holding the locking member in its locked position.
34. A system according to claim 33 wherein the locking member engagement surface comprises a tab that extends into the hollow channel and wherein a notch is formed in the locking member such that when the locking member is advanced to its locked position the tab will seat in the notch, thereby holding the locking member in its locked position.
35. A system according to claim 28 wherein:
the second anchor comprises an elongate tubular member having an open proximal end and a side aperture;
wherein the hollow passage extends at least from the open proximal end to the side aperture such that the proximal end of the connector may be inserted into the side aperture and the second anchor may then be advanced over the connector such that the connector trails out of the open proximal end of the second anchor as the second anchor is advanced over the connector.
36. A system according to claim 1 wherein the second introducer further comprises a cutter for cutting the connector at a site proximal to the second anchor after the second anchor has been advanced to the second location.
37. A system according to claim 36 further comprising a handpiece on the proximal end of the elongate shaft, said handpiece comprising a first actuator for advancing the second anchor over the connector, a second actuator for locking the second anchor on the connector and a third actuator for cutting the connector.
38. A system according to claim 1 further comprising a handpiece on the proximal end of the elongate shaft, said handpiece comprising a first actuator for advancing the second anchor over the connector and a second actuator for locking the second anchor on the connector.
39. A system according to claim 1 wherein the second anchor has a hollow passage through which the connector is passed and wherein the second introducer further comprises a crimping device for crimping the second anchor to lock the second anchor on the connector at the second location.