IP Library Granted Patent US 7,955,617
Granted Patent B2
US 7,955,617 · App. 11/834,493 · Granted Jun 7, 2011

Traumatic brain injury biomarker diagnostic

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Quick Facts
Patent No.
US 7,955,617
App. No.
11/834,493
Granted
Jun 7, 2011
Kind
B2
Abstract

Blast Induced Traumatic Brain Injury or bTBI needs objective and subjective testing that can be made quickly in the field. Subjective tests using shapes, textures, tastes and odors as disposable, edible candies on a stick may be carried in a field kit. An objective test that employs a similar candy on a stick bearing antibodies bound to bioluminescent marker reads whether molecules believed to be released into the mouth from an injured brain are present if they bind to the specific antibody which may then be read.

Claims (16)

1. A diagnostic device for assessing brain injury, comprising:

a) a candy lollypop consisting of candy on a disposable stick;

b) the candy lollypop including an antibody to a biomarker for brain damage, said biomarker being glutamate, bound to the bioluminescence compound luciferin.

2. The diagnostic device of claim 1 , wherein the candy lollypop is made in a stereoagnosis form for assessing damage to the facial or trigeminal nerve.

3. The diagnostic device of claim 1 , wherein the candy lollypop includes a defined taste selected from the group consisting of sweet, salty, bitter and sour, for assessing damage to the facial nerve.

4. The diagnostic device of claim 1 , wherein the candy lollypop includes a defined smell for assessing damage to the olfactory nerve.

5. A field test kit for assessing possible brain injury including:

a) a disposable lollypop consisting of a candy on a stick in a stereoagnosis form;

b) a disposable lollypop consisting of a candy on a stick with a defined taste selected from the group consisting of sweet, salty, bitter and sour incorporated therein;

c) a disposable lollypop consisting of a candy on a stick with a defined smell incorporated therein;

d) a disposable lollypop consisting of a candy on a stick with an antibody to the biomarker for brain damage glutamate bound to a bioluminescence compound; and

e) instructions regarding the use of the lollypop tests.

6. A field test kit for assessing possible brain injury comprising:

a) a disposable lollypop consisting of a candy on a stick with an antibody to the biomarker for brain damage glutamate bound to a bioluminescence compound; and

b) instructions regarding the use of the lollypop test.

7. The field kit of claim 6 wherein said bioluminescence compound is a luciferin.

Assignments (10)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 10, 2021
From: NORTHROP GRUMMAN INNOVATION SYSTEMS LLC
To: NORTHROP GRUMMAN SYSTEMS CORPORATION
Reel/Frame 055215/0559 →
CHANGE OF NAME Recorded Feb 1, 2021
From: NORTHROP GRUMMAN INNOVATION SYSTEMS, INC.
To: NORTHROP GRUMMAN INNOVATION SYSTEMS LLC
Reel/Frame 055191/0490 →
CHANGE OF NAME Recorded Dec 17, 2020
From: ORBITAL ATK, INC.
To: NORTHROP GRUMMAN INNOVATION SYSTEMS, INC.
Reel/Frame 054799/0623 →
TERMINATION AND RELEASE OF SECURITY INTEREST IN PATENTS Recorded Jun 6, 2018
From: WELLS FARGO BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT
To: ORBITAL ATK, INC.
Reel/Frame 046477/0874 →
CHANGE OF NAME Recorded Sep 14, 2017
From: ALLIANT TECHSYSTEMS INC.
To: ORBITAL ATK, INC.
Reel/Frame 043865/0372 →
RELEASE OF SECURITY INTEREST Recorded Oct 8, 2015
From: BANK OF AMERICA, N.A.
To: ALLIANT TECHSYSTEMS INC.; FEDERAL CARTRIDGE CO.; EAGLE INDUSTRIES UNLIMITED, INC.; AMMUNITION ACCESSORIES, INC.; ORBITAL ATK, INC. (F/K/A ALLIANT TECHSYSTEMS INC.)
Reel/Frame 036816/0624 →
SECURITY AGREEMENT Recorded Sep 30, 2015
From: ORBITAL ATK, INC.; ORBITAL SCIENCES CORPORATION
To: WELLS FARGO BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT
Reel/Frame 036732/0170 →
SECURITY AGREEMENT Recorded Nov 26, 2013
From: ALLIANT TECHSYSTEMS INC.; CALIBER COMPANY; EAGLE INDUSTRIES UNLIMITED, INC.; FEDERAL CARTRIDGE COMPANY; SAVAGE ARMS, INC.; SAVAGE RANGE SYSTEMS, INC.; SAVAGE SPORTS CORPORATION
To: BANK OF AMERICA, N.A.
Reel/Frame 031731/0281 →
SECURITY AGREEMENT Recorded Nov 4, 2010
From: ALLIANT TECHSYSTEMS INC.; AMMUNITION ACCESSORIES INC.; ATK COMMERCIAL AMMUNITION COMPANY INC.; ATK COMMERCIAL AMMUNITION HOLDINGS COMPANY; ATK LAUNCH SYSTEMS INC.; ATK SPACE SYSTEMS INC.; FEDERAL CARTRIDGE COMPANY; EAGLE INDUSTRIES UNLIMITED, INC.; EAGLE MAYAGUEZ, LLC; EAGLE NEW BEDFORD, INC.
To: BANK OF AMERICA, N.A.
Reel/Frame 025321/0291 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 9, 2008
From: KARRON, DANIEL B.; EISLER, ROBERT D.
To: ALLIANT TECHSYSTEMS INC.
Reel/Frame 020343/0009 →