Devices for reducing the size of an internal tissue opening
A medical system for treating an internal tissue opening can include a closure device and associated delivery device. The closure device can include a body portion operatively associated with a first anchor and a second anchor. The body portion can include a plurality of segments defining a multi-cellular structure. A segment can define a variable width along a length of the segment to have a substantially equal stress level along the length when deflected. The closure device can be configured to apply lateral force to tissue of the internal tissue opening to bring tissue together for closure. The closure device can have a substantially flat aspect, and have a depth thickness that is substantially greater than the thickness or width of a majority of the members forming the closure device. The closure device can also include a member adapted to induce tissue growth.
1. A medical device deployable at least partially within a hole defined in a tissue structure, the hole defining an axis oriented axially through the hole, the medical device comprising:
a catheter configured to be positioned adjacent the hole defined in the tissue structure; and
a framework configured to maintain a substantially flat configuration as said framework transitions and self-expands from a non-deployed state within the catheter to an intended, as deployed state from the catheter, said framework oriented substantially parallel to, or extending substantially along, the axis of the hole when in the intended, as deployed state within the tissue structure, said framework comprising a central portion and at least one anchor extending from said central portion, said central portion including central frame struts having a length and a width, wherein the width of at least one of said central frame struts varies along at least a portion of the length of said at least one of said central frame struts in a tapered configuration, said tapered configuration tapering to a tapered end such that said tapered end directly interconnects to another portion of the framework.
2. A medical device as recited in claim 1 , wherein said central portion is configured to preferentially expand from a collapsed orientation to the state for intended deployment within the tissue structure.
3. A medical device as recited in claim 1 , wherein said framework comprises a multi-cellular structure.
4. A medical device as recited in claim 1 , wherein said central frame struts have substantially equal lengths.
5. A medical device as recited in claim 1 , wherein said at least one central frame struts is configured to have a substantially uniform stress along said at least a portion of said length when deflected.
6. A medical device as recited in claim 1 , further comprising a tissue growth promoting member associated with the framework.
7. A medical device as recited in claim 6 , wherein said tissue growth promoting member is attached to said framework such that said tissue growth promoting member extends substantially out of plane from said substantially flat configuration.
8. A medical device deployable at least partially within a hole defined in a tissue structure, the hole defining an axis oriented axially through the hole, the medical device comprising:
a catheter configured to be positioned adjacent the hole defined in the tissue structure; and
a framework configured to maintain a substantially flat configuration as said framework transitions and self-expands from a non-deployed state within the catheter to an intended, as deployed state from the catheter, said framework oriented substantially parallel to, or extending substantially along, the axis of the hole when in the intended, as deployed state within the tissue structure, said framework comprising a central portion and at least one anchor extending from said central portion, said central portion including a plurality of central frame periphery struts defining a central frame periphery and a plurality of central frame internal struts extending internally from the central frame periphery, the central frame periphery struts and the central frame internal struts defining a multi-cellular structure of the central portion of the framework, at least one of said plurality of central frame internal struts including a first strut portion and a second strut portion, said first strut portion having a greater rigidity than said second strut portion.
9. A medical device as recited in claim 8 , wherein said central portion comprises a multi-cellular structure.
10. A medical device as recited in claim 8 , wherein said central portion is adapted to apply lateral force to the tissue of the tissue structure.
11. A medical device as recited in claim 8 , further comprising a tissue growth promoting member associated with said framework.
12. A medical device as recited in claim 11 , wherein said tissue growth promoting member is attached to said framework such that said tissue growth promoting member extends substantially out of plane from said substantially flat configuration.
13. A medical device as recited in claim 8 , wherein said first strut portion has a width that is greater than the width of said second strut portion.
14. A medical device as recited in claim 8 , wherein said at least one anchor comprises a first anchor and a second anchor, said first anchor configured to extend in a first atrium adjacent the tissue structure and said second anchor configured to extend in a second atrium adjacent the tissue structure, the first anchor and the second anchor having structures that are substantially coplanar with each other.
15. A medical device as recited in claim 8 , wherein said central frame internal struts of said central portion comprise substantially equal lengths.
16. A medical device deployable at least partially within a hole defined in a tissue structure, the hole defining an axis oriented axially through the hole, the medical device comprising:
a catheter configured to be positioned adjacent the hole defined in the tissue structure; and
a framework configured to maintain a substantially flat configuration as said frame transitions and self-expands from a non-deployed state within the catheter to an intended, as deployed state from the catheter, said framework oriented substantially parallel to, or extending substantially along, the axis of the hole when in the intended, as deployed state within the tissue structure, said framework comprising a central portion and at least one anchor extending from said central portion, said central portion including central frame struts, at least one of said central frame struts including a longitudinal length dimension and having an aspect ratio of a depth dimension to a lateral width dimension of at least 2 to 1, wherein said depth dimension is defined to extend substantially perpendicular relative to said substantially flat configuration of said framework.
17. A medical device as recited in claim 16 , further comprising a tissue growth promoting member associated with the framework.
18. A medical device as recited in claim 17 , wherein said tissue growth promoting member is attached to said framework such that said tissue growth promoting member extends substantially out of plane from said substantially flat configuration.
19. A medical device as recited in claim 16 , further comprising a second anchor operably associated with said central portion, wherein said first anchor comprises a proximal anchor and wherein said second anchor comprises a distal anchor.
20. A medical device as recited in claim 16 , wherein said aspect ratio is between about 2:1 and 10:1.
21. A medical device as recited in claim 16 , wherein said aspect ratio is about 4:1.
22. A medical device as recited in claim 16 , wherein said central frame struts are configured to resist movement out of plane of the substantially flat configuration.
23. A medical device as recited in claim 16 , wherein said central portion comprises a multi-cellular structure.