Devices and methods for treatment of ocular disorders
View Patent ↗Intraocular implants and delivery instruments are disclosed for treating ophthalmic conditions and ocular disorders, such as glaucoma. The implants are configured to extend between the anterior chamber of the eye and a fluid outflow path or physiologic outflow pathway, such as Schlemm's canal, of the eye for enhancing outflow of aqueous from the anterior chamber so as to reduce intraocular pressure. The implants can have features for anchoring the implant into the physiologic outflow pathway as well as preventing the walls of the physiologic outflow pathway from closing the outlet of the implants. The delivery instruments can be steerable so as to make implantation easier. Additionally, the delivery instruments can be configured to hold a plurality of implants so that multiple implants can be implanted through one incision without removing the delivery instrument from the incision between serial implantations.
1. A method of implanting a plurality of implants for treating an ocular disorder, comprising:
inserting an instrument into an eye through an incision;
providing a plurality of biocompatible implants that, when implanted, convey aqueous humor from an anterior chamber of the eye to a fluid outflow path of the eye so as to reduce intraocular pressure;
utilizing said instrument to deliver a first biocompatible implant through a wall of Schlemm's canal at a first location; and
utilizing said instrument to deliver a second biocompatible implant through a wall of Schlemm's canal at a second location, without removing said instrument from the eye between said deliveries of said implants;
wherein said deliveries of said implants comprises piercing eye tissue adjacent to Schlemm's canal.
2. The method of claim 1 , further comprising determining said locations with reference to morphological data on collector channel locations.
3. The method of claim 1 , wherein the incision is a superiorly located limbal incision.
4. The method of claim 3 , wherein the incision is between 10 o'clock and 2 o'clock.
5. The method of claim 1 , further comprising performing cataract surgery through said incision.
6. The method of claim 1 , further comprising determining said locations by imaging collector channel locations.
7. The method of claim 1 , wherein said implants are delivered through a trabecular meshwork of said eye.
8. The method of claim 1 , wherein said locations are angularly spaced along Schlemm's canal by at least 20 degrees.
9. The method of claim 1 , wherein the first and second locations are substantially at collector channels.
10. The method of claim 1 , wherein said implants have different flow characteristics.
11. The method of claim 1 , wherein one of said first and second locations is nasal and the other of said first and second locations is temporal.
12. The method of claim 1 , wherein at least one of said first and second locations is at a collector channel.
13. The method of claim 1 , wherein piercing eye tissue involves advancing a sharpened member of the instrument into said eye tissue.
14. The method of claim 13 additionally comprising advancing at least one of the implants over the sharpened member to the corresponding first or second location.
15. A method of implanting a plurality of implants for treating an ocular disorder, comprising:
inserting an instrument into an eye through an incision;
utilizing said instrument to deliver a first biocompatible implant through a wall of Schlemm's canal at a first location; and
utilizing said instrument to deliver a second biocompatible implant through a wall of Schlemm's canal at a second location;
wherein said locations are determined from morphological data on a collector channel and said first and second locations are angularly spaced along Schlemm's canal by at least 20 degrees.
16. The method of claim 15 , wherein at least one of said first and second locations is at a collector channel.
17. A method of implanting a plurality of implants for treating an ocular disorder, comprising:
inserting an instrument into an eye through an incision;
positioning said instrument at a first location and utilizing a cutting edge of said instrument to pierce eye tissue adjacent a posterior segment of the eye;
utilizing said instrument to deliver a first implant into the posterior segment of the eye at said first location; and
moving said instrument to a second location and utilizing said instrument to deliver a second implant into the posterior segment of the eye at the second location, without removing said instrument from the eye between said deliveries of said implants.
18. The method of claim 17 , wherein piercing eye tissue involves advancing a sharpened member of the instrument into said eye tissue.
19. The method of claim 18 additionally comprising advancing at least one of the implants over the sharpened member to the corresponding first or second location.