Granted Patent
B2
US 7,449,587 · App. 11/839,565 · Granted Nov 11, 2008
Process for the synthesis of peptides containing a 4-hydroxy-proline substructure
Assignee:
Novartis AG
View Patent ↗
Loading inventors, assignments & file history…
Abstract
The present invention relates to processes for preparing peptides and to intermediates involved in such processes, e.g. a process for preparing a compound of formula VIII wherein R 12 and R 13 are as defined herein.
Claims (5)
1. A compound of formula XIV
wherein R 16 is a removable protecting group other than fluorenylmethoxycarbonyl, and is different to R 18 ;
R 17 is hydrogen or a blocking group removable by hydrolysis or hydrogenolysis; and
R 18 is hydrogen or a removable protecting group other than fluorenylmethoxycarbonyl.
2. A compound according to claim 1 , wherein R 16 is tert-butoxycarbonyl.
Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Feb 27, 2020
From: NOVARTIS AG
To: RECORDATI AG
Reel/Frame 051945/0630 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Feb 14, 2020
From: WIETFELD, BERNHARD; PRIKOSZOVICH, WALTER; ERB, BERNHARD; PACHINGER, WERNER
To: NOVARTIS AG
Reel/Frame 051819/0889 →
Priority Claims (2)
GB 0229020.3
· Dec 12, 2002
· national
GB 0229280.3
· Dec 16, 2002
· national
Continuity (2)
Division
1053802800